Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors
Mitochondrial transport toward both the plus- and minus-ends of microtubules is mediated by motor proteins linked to mitochondria by TRAK adaptor proteins. Here the authors investigate the role of TRAK2 as a bidirectional motor adaptor, and propose a model where TRAK2 coordinates the activities of o...
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Autores principales: | Adam R. Fenton, Thomas A. Jongens, Erika L. F. Holzbaur |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/acb6e48bd1c84d51b3fcfa57aca067cf |
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