Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution

Microtubule dynamics are essential for axonal transport. InC. elegans, the authors show that dynein heavy chain regulates the spatial distribution of dendritic microtubules which ensures correct transport progression.

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Autores principales:	Shaul Yogev, Celine I. Maeder, Roshni Cooper, Mark Horowitz, Adam G. Hendricks, Kang Shen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/acbd2dc35519436e934590589aaef8f4
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spelling	oai:doaj.org-article:acbd2dc35519436e934590589aaef8f42021-12-02T14:42:42ZLocal inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution10.1038/ncomms150632041-1723https://doaj.org/article/acbd2dc35519436e934590589aaef8f42017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15063https://doaj.org/toc/2041-1723Microtubule dynamics are essential for axonal transport. InC. elegans, the authors show that dynein heavy chain regulates the spatial distribution of dendritic microtubules which ensures correct transport progression.Shaul YogevCeline I. MaederRoshni CooperMark HorowitzAdam G. HendricksKang ShenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shaul Yogev Celine I. Maeder Roshni Cooper Mark Horowitz Adam G. Hendricks Kang Shen Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
description	Microtubule dynamics are essential for axonal transport. InC. elegans, the authors show that dynein heavy chain regulates the spatial distribution of dendritic microtubules which ensures correct transport progression.
format	article
author	Shaul Yogev Celine I. Maeder Roshni Cooper Mark Horowitz Adam G. Hendricks Kang Shen
author_facet	Shaul Yogev Celine I. Maeder Roshni Cooper Mark Horowitz Adam G. Hendricks Kang Shen
author_sort	Shaul Yogev
title	Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
title_short	Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
title_full	Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
title_fullStr	Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
title_full_unstemmed	Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
title_sort	local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/acbd2dc35519436e934590589aaef8f4
work_keys_str_mv	AT shaulyogev localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution AT celineimaeder localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution AT roshnicooper localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution AT markhorowitz localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution AT adamghendricks localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution AT kangshen localinhibitionofmicrotubuledynamicsbydyneinisrequiredforneuronalcargodistribution
_version_	1718389652505755648

Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution

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