Ocular Involvement in Relapsing Polychondritis

Relapsing polychondritis (RPC) is a rare systemic immune-mediated disease characterized by recurrent inflammation of cartilaginous and proteoglycan-rich tissues throughout the body. Auricular, nasal, tracheal, and articular chondritis and arthritis are common systemic symptoms in patients with RPC....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ken Fukuda, Tomoka Mizobuchi, Isana Nakajima, Tatsuma Kishimoto, Yusaku Miura, Yoshinori Taniguchi
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	relapsing polychondritis scleritis uveitis keratitis conjunctivitis retinopathy Medicine R
Acceso en línea:	https://doaj.org/article/acc6357179c24d47adb5ef0be490673e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:acc6357179c24d47adb5ef0be490673e
record_format	dspace
spelling	oai:doaj.org-article:acc6357179c24d47adb5ef0be490673e2021-11-11T17:36:16ZOcular Involvement in Relapsing Polychondritis10.3390/jcm102149702077-0383https://doaj.org/article/acc6357179c24d47adb5ef0be490673e2021-10-01T00:00:00Zhttps://www.mdpi.com/2077-0383/10/21/4970https://doaj.org/toc/2077-0383Relapsing polychondritis (RPC) is a rare systemic immune-mediated disease characterized by recurrent inflammation of cartilaginous and proteoglycan-rich tissues throughout the body. Auricular, nasal, tracheal, and articular chondritis and arthritis are common systemic symptoms in patients with RPC. Ocular tissues are also targets of inflammation in RPC, and a variety of ocular symptoms are observed in approximately half of the patients with RPC. Scleritis/episcleritis, uveitis, and conjunctivitis are common symptoms associated with RPC. Less frequently, keratitis, retinopathy, optic neuropathy, muscle palsy, and orbital inflammation are also observed. Ocular inflammation could also be the first manifestation of RPC. Although RPC is a potentially fatal and sight-threatening disease, the rarity of the disease and its protean clinical presentation may lead to delayed diagnosis or misdiagnosis. Given the high prevalence of ocular involvement in RPC, to avoid misdiagnosis, physicians should be suspicious of RPC when they see patients with recurrent ocular inflammatory conditions and various systemic symptoms. In this article, we provide a comprehensive review of ocular manifestations associated with RPC.Ken FukudaTomoka MizobuchiIsana NakajimaTatsuma KishimotoYusaku MiuraYoshinori TaniguchiMDPI AGarticlerelapsing polychondritisscleritisuveitiskeratitisconjunctivitisretinopathyMedicineRENJournal of Clinical Medicine, Vol 10, Iss 4970, p 4970 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	relapsing polychondritis scleritis uveitis keratitis conjunctivitis retinopathy Medicine R
spellingShingle	relapsing polychondritis scleritis uveitis keratitis conjunctivitis retinopathy Medicine R Ken Fukuda Tomoka Mizobuchi Isana Nakajima Tatsuma Kishimoto Yusaku Miura Yoshinori Taniguchi Ocular Involvement in Relapsing Polychondritis
description	Relapsing polychondritis (RPC) is a rare systemic immune-mediated disease characterized by recurrent inflammation of cartilaginous and proteoglycan-rich tissues throughout the body. Auricular, nasal, tracheal, and articular chondritis and arthritis are common systemic symptoms in patients with RPC. Ocular tissues are also targets of inflammation in RPC, and a variety of ocular symptoms are observed in approximately half of the patients with RPC. Scleritis/episcleritis, uveitis, and conjunctivitis are common symptoms associated with RPC. Less frequently, keratitis, retinopathy, optic neuropathy, muscle palsy, and orbital inflammation are also observed. Ocular inflammation could also be the first manifestation of RPC. Although RPC is a potentially fatal and sight-threatening disease, the rarity of the disease and its protean clinical presentation may lead to delayed diagnosis or misdiagnosis. Given the high prevalence of ocular involvement in RPC, to avoid misdiagnosis, physicians should be suspicious of RPC when they see patients with recurrent ocular inflammatory conditions and various systemic symptoms. In this article, we provide a comprehensive review of ocular manifestations associated with RPC.
format	article
author	Ken Fukuda Tomoka Mizobuchi Isana Nakajima Tatsuma Kishimoto Yusaku Miura Yoshinori Taniguchi
author_facet	Ken Fukuda Tomoka Mizobuchi Isana Nakajima Tatsuma Kishimoto Yusaku Miura Yoshinori Taniguchi
author_sort	Ken Fukuda
title	Ocular Involvement in Relapsing Polychondritis
title_short	Ocular Involvement in Relapsing Polychondritis
title_full	Ocular Involvement in Relapsing Polychondritis
title_fullStr	Ocular Involvement in Relapsing Polychondritis
title_full_unstemmed	Ocular Involvement in Relapsing Polychondritis
title_sort	ocular involvement in relapsing polychondritis
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/acc6357179c24d47adb5ef0be490673e
work_keys_str_mv	AT kenfukuda ocularinvolvementinrelapsingpolychondritis AT tomokamizobuchi ocularinvolvementinrelapsingpolychondritis AT isananakajima ocularinvolvementinrelapsingpolychondritis AT tatsumakishimoto ocularinvolvementinrelapsingpolychondritis AT yusakumiura ocularinvolvementinrelapsingpolychondritis AT yoshinoritaniguchi ocularinvolvementinrelapsingpolychondritis
_version_	1718432083864453120

Ocular Involvement in Relapsing Polychondritis

Ejemplares similares