Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer

Patwa, Yamashita et al. utilize multiplexed imaging to demonstrate that profiling cell-to-cell interactions in the microenvironment can reveal predictors of recurrence and overall survival in triple-negative breast cancer, especially highlighting the relevance of immunoregulatory proteins. The autho...

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Autores principales:	Aalok Patwa, Rikiya Yamashita, Jin Long, Tyler Risom, Michael Angelo, Leeat Keren, Daniel L. Rubin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/accef0e4e5044d8990a14811008e28a2
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spelling	oai:doaj.org-article:accef0e4e5044d8990a14811008e28a22021-12-02T15:22:55ZMultiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer10.1038/s42003-021-02361-12399-3642https://doaj.org/article/accef0e4e5044d8990a14811008e28a22021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02361-1https://doaj.org/toc/2399-3642Patwa, Yamashita et al. utilize multiplexed imaging to demonstrate that profiling cell-to-cell interactions in the microenvironment can reveal predictors of recurrence and overall survival in triple-negative breast cancer, especially highlighting the relevance of immunoregulatory proteins. The authors also use multivariate analysis to provide additional prognostic information compared to clinical variables.Aalok PatwaRikiya YamashitaJin LongTyler RisomMichael AngeloLeeat KerenDaniel L. RubinNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Aalok Patwa Rikiya Yamashita Jin Long Tyler Risom Michael Angelo Leeat Keren Daniel L. Rubin Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
description	Patwa, Yamashita et al. utilize multiplexed imaging to demonstrate that profiling cell-to-cell interactions in the microenvironment can reveal predictors of recurrence and overall survival in triple-negative breast cancer, especially highlighting the relevance of immunoregulatory proteins. The authors also use multivariate analysis to provide additional prognostic information compared to clinical variables.
format	article
author	Aalok Patwa Rikiya Yamashita Jin Long Tyler Risom Michael Angelo Leeat Keren Daniel L. Rubin
author_facet	Aalok Patwa Rikiya Yamashita Jin Long Tyler Risom Michael Angelo Leeat Keren Daniel L. Rubin
author_sort	Aalok Patwa
title	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
title_short	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
title_full	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
title_fullStr	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
title_full_unstemmed	Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
title_sort	multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/accef0e4e5044d8990a14811008e28a2
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Multiplexed imaging analysis of the tumor-immune microenvironment reveals predictors of outcome in triple-negative breast cancer

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