Application of liposomes in drug development – focus on gastroenterological targets

Jian-Xin Zhang,1 Kun Wang,1 Zheng-Fa Mao,1 Xin Fan,1 De-Li Jiang,2 Min Chen,2 Lei Cui,1 Kang Sun,1 Sheng-Chun Dang1 1Department of General Surgery, the Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China; 2School of Chemistry and Chemical Engine...

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Autores principales:	Zhang JX, Wang K, Mao ZF, Fan X, Jiang DL, Chen M, Cui L, Sun K, Dang SC
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/acd226518d15447d9467a31a01e651b0
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spelling	oai:doaj.org-article:acd226518d15447d9467a31a01e651b02021-12-02T03:03:57ZApplication of liposomes in drug development – focus on gastroenterological targets1176-91141178-2013https://doaj.org/article/acd226518d15447d9467a31a01e651b02013-04-01T00:00:00Zhttp://www.dovepress.com/application-of-liposomes-in-drug-development-ndash-focus-on-gastroente-a12687https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Jian-Xin Zhang,1 Kun Wang,1 Zheng-Fa Mao,1 Xin Fan,1 De-Li Jiang,2 Min Chen,2 Lei Cui,1 Kang Sun,1 Sheng-Chun Dang1 1Department of General Surgery, the Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China; 2School of Chemistry and Chemical Engineering of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China Abstract: Over the past decade, liposomes became a focal point in developing drug delivery systems. New liposomes, with novel lipid molecules or conjugates, and new formulations opened possibilities for safely and efficiently treating many diseases including cancers. New types of liposomes can prolong circulation time or specifically deliver drugs to therapeutic targets. This article concentrates on current developments in liposome based drug delivery systems for treating diseases of the gastrointestinal tract. We will review different types and uses of liposomes in the development of therapeutics for gastrointestinal diseases including inflammatory bowel diseases and colorectal cancer. Keywords: liposome, colorectal cancer, inflammatory bowel disease, drug deliveryZhang JXWang KMao ZFFan XJiang DLChen MCui LSun KDang SCDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 1325-1334 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Zhang JX Wang K Mao ZF Fan X Jiang DL Chen M Cui L Sun K Dang SC Application of liposomes in drug development – focus on gastroenterological targets
description	Jian-Xin Zhang,1 Kun Wang,1 Zheng-Fa Mao,1 Xin Fan,1 De-Li Jiang,2 Min Chen,2 Lei Cui,1 Kang Sun,1 Sheng-Chun Dang1 1Department of General Surgery, the Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China; 2School of Chemistry and Chemical Engineering of Jiangsu University, Zhenjiang, Jiangsu Province, People's Republic of China Abstract: Over the past decade, liposomes became a focal point in developing drug delivery systems. New liposomes, with novel lipid molecules or conjugates, and new formulations opened possibilities for safely and efficiently treating many diseases including cancers. New types of liposomes can prolong circulation time or specifically deliver drugs to therapeutic targets. This article concentrates on current developments in liposome based drug delivery systems for treating diseases of the gastrointestinal tract. We will review different types and uses of liposomes in the development of therapeutics for gastrointestinal diseases including inflammatory bowel diseases and colorectal cancer. Keywords: liposome, colorectal cancer, inflammatory bowel disease, drug delivery
format	article
author	Zhang JX Wang K Mao ZF Fan X Jiang DL Chen M Cui L Sun K Dang SC
author_facet	Zhang JX Wang K Mao ZF Fan X Jiang DL Chen M Cui L Sun K Dang SC
author_sort	Zhang JX
title	Application of liposomes in drug development – focus on gastroenterological targets
title_short	Application of liposomes in drug development – focus on gastroenterological targets
title_full	Application of liposomes in drug development – focus on gastroenterological targets
title_fullStr	Application of liposomes in drug development – focus on gastroenterological targets
title_full_unstemmed	Application of liposomes in drug development – focus on gastroenterological targets
title_sort	application of liposomes in drug development – focus on gastroenterological targets
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/acd226518d15447d9467a31a01e651b0
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Application of liposomes in drug development &ndash; focus on gastroenterological targets

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Application of liposomes in drug development – focus on gastroenterological targets