Cyclic nucleotide dependent dephosphorylation of regulator of G-protein signaling 18 in human platelets.
Regulator of G-protein signaling 18 (RGS18) is a GTPase-activating protein that turns off Gq signaling in platelets. RGS18 is regulated by binding to the adaptor protein 14-3-3 via phosphorylated serine residues S49 and S218 on RGS18. In this study we confirm that thrombin, thromboxane A2, or ADP st...
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Autores principales: | Kristina Gegenbauer, Zoltan Nagy, Albert Smolenski |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
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Materias: | |
Acceso en línea: | https://doaj.org/article/acd9242442494ee2b89a8b6f3631abe1 |
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