Polyunsaturated fatty acid production by Yarrowia lipolytica employing designed myxobacterial PUFA synthases

Sustainable sources are needed to meet the demand for long-chain polyunsaturated fatty acids. Here the authors construct an artificial biosynthetic gene cluster in Y. lipolytica capable of producing a high concentration of PUFAs.

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Detalles Bibliográficos
Autores principales: Katja Gemperlein, Demian Dietrich, Michael Kohlstedt, Gregor Zipf, Hubert S. Bernauer, Christoph Wittmann, Silke C. Wenzel, Rolf Müller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ace1af233c2740f59272853e227a43e3
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Descripción
Sumario:Sustainable sources are needed to meet the demand for long-chain polyunsaturated fatty acids. Here the authors construct an artificial biosynthetic gene cluster in Y. lipolytica capable of producing a high concentration of PUFAs.