Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration

The extracellular matrix contributes to tissue regeneration by binding and releasing growth factors. Here the authors present the jigsaw-shaped self-assembling peptide JigSAP as an artificial ECM and show that VEGF-JigSAP has therapeutic effects on the subacute-chronic phase of brain stroke.

Guardado en:

Detalles Bibliográficos
Autores principales:	Atsuya Yaguchi, Mio Oshikawa, Go Watanabe, Hirotsugu Hiramatsu, Noriyuki Uchida, Chikako Hara, Naoko Kaneko, Kazunobu Sawamoto, Takahiro Muraoka, Itsuki Ajioka
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ace4d5be898e4312b4bf35de4601f775
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ace4d5be898e4312b4bf35de4601f775
record_format	dspace
spelling	oai:doaj.org-article:ace4d5be898e4312b4bf35de4601f7752021-11-21T12:38:52ZEfficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration10.1038/s41467-021-26896-32041-1723https://doaj.org/article/ace4d5be898e4312b4bf35de4601f7752021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26896-3https://doaj.org/toc/2041-1723The extracellular matrix contributes to tissue regeneration by binding and releasing growth factors. Here the authors present the jigsaw-shaped self-assembling peptide JigSAP as an artificial ECM and show that VEGF-JigSAP has therapeutic effects on the subacute-chronic phase of brain stroke.Atsuya YaguchiMio OshikawaGo WatanabeHirotsugu HiramatsuNoriyuki UchidaChikako HaraNaoko KanekoKazunobu SawamotoTakahiro MuraokaItsuki AjiokaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Atsuya Yaguchi Mio Oshikawa Go Watanabe Hirotsugu Hiramatsu Noriyuki Uchida Chikako Hara Naoko Kaneko Kazunobu Sawamoto Takahiro Muraoka Itsuki Ajioka Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
description	The extracellular matrix contributes to tissue regeneration by binding and releasing growth factors. Here the authors present the jigsaw-shaped self-assembling peptide JigSAP as an artificial ECM and show that VEGF-JigSAP has therapeutic effects on the subacute-chronic phase of brain stroke.
format	article
author	Atsuya Yaguchi Mio Oshikawa Go Watanabe Hirotsugu Hiramatsu Noriyuki Uchida Chikako Hara Naoko Kaneko Kazunobu Sawamoto Takahiro Muraoka Itsuki Ajioka
author_facet	Atsuya Yaguchi Mio Oshikawa Go Watanabe Hirotsugu Hiramatsu Noriyuki Uchida Chikako Hara Naoko Kaneko Kazunobu Sawamoto Takahiro Muraoka Itsuki Ajioka
author_sort	Atsuya Yaguchi
title	Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
title_short	Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
title_full	Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
title_fullStr	Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
title_full_unstemmed	Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
title_sort	efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ace4d5be898e4312b4bf35de4601f775
work_keys_str_mv	AT atsuyayaguchi efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT miooshikawa efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT gowatanabe efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT hirotsuguhiramatsu efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT noriyukiuchida efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT chikakohara efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT naokokaneko efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT kazunobusawamoto efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT takahiromuraoka efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration AT itsukiajioka efficientproteinincorporationandreleasebyajigsawshapedselfassemblingpeptidehydrogelforinjuredbrainregeneration
_version_	1718418907420688384

Efficient protein incorporation and release by a jigsaw-shaped self-assembling peptide hydrogel for injured brain regeneration

Ejemplares similares