Fine-mapping and cell-specific enrichment at corneal resistance factor loci prioritize candidate causal regulatory variants
Here, the authors report a genome-wide association analysis for corneal resistance factor (CRF), a measure of corneal biomechanical properties relevant to a number of corneal diseases. They identify 135 loci associated with CRF and use fine-mapping and ATAC-seq in human cornea cell lines to identify...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/acf6f0549b5e4be2b8d0c1d371bee340 |
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