Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review

Justin C Muste, Matthew W Russell, Rishi P Singh Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USACorrespondence: Rishi P SinghCenter for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, i-32, Cleveland, OH, 44195, USAEm...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Muste JC, Russell MW, Singh RP
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	photobiomodulation therapy age-related macular degeneration diabetic macular edema diabetic retinopathy Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/acfc425f5696496091f27e67a9a74076
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:acfc425f5696496091f27e67a9a74076
record_format	dspace
spelling	oai:doaj.org-article:acfc425f5696496091f27e67a9a740762021-12-02T16:39:04ZPhotobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review1177-5483https://doaj.org/article/acfc425f5696496091f27e67a9a740762021-09-01T00:00:00Zhttps://www.dovepress.com/photobiomodulation-therapy-for-age-related-macular-degeneration-and-di-peer-reviewed-fulltext-article-OPTHhttps://doaj.org/toc/1177-5483Justin C Muste, Matthew W Russell, Rishi P Singh Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USACorrespondence: Rishi P SinghCenter for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, i-32, Cleveland, OH, 44195, USAEmail singhr@ccf.orgPurpose: Photobiomodulation therapy (PBT) has emerged as a possible treatment for age-related macular degeneration (AMD) and diabetic retinopathy (DR). This review seeks to summarize the application of PBT in AMD and DR.Methods: The National Clinical Trial (NCT) database and PubMed were queried using a literature search strategy and reviewed by the authors.Results: Fourteen studies examining the application of PBT for AMD and nine studies examining the application of PBT for diabetic macular edema (DME) were extracted from 60 candidate publications.Discussion: Despite notable methodological differences between studies, PBT has been reported to treat certain DR and AMD patients. DR patients with center involving DME and VA ≥ 20/25 have demonstrated response to treatment. AMD patients at Age-Related Eye Disease Study Stages 2– 4 with VA ≥ 20/200 have also shown response to treatment. Results of major clinical trials are pending.Conclusion: PBT remains an emergent therapy with possible applications in DR and AMD. Further, high powered studies monitored by a neutral party with standard devices, treatment delivery and treatment timing are needed.Keywords: photobiomodulation therapy, age-related macular degeneration, diabetic macular edema, diabetic retinopathyMuste JCRussell MWSingh RPDove Medical Pressarticlephotobiomodulation therapyage-related macular degenerationdiabetic macular edemadiabetic retinopathyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 3709-3720 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	photobiomodulation therapy age-related macular degeneration diabetic macular edema diabetic retinopathy Ophthalmology RE1-994
spellingShingle	photobiomodulation therapy age-related macular degeneration diabetic macular edema diabetic retinopathy Ophthalmology RE1-994 Muste JC Russell MW Singh RP Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
description	Justin C Muste, Matthew W Russell, Rishi P Singh Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USACorrespondence: Rishi P SinghCenter for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Ave, i-32, Cleveland, OH, 44195, USAEmail singhr@ccf.orgPurpose: Photobiomodulation therapy (PBT) has emerged as a possible treatment for age-related macular degeneration (AMD) and diabetic retinopathy (DR). This review seeks to summarize the application of PBT in AMD and DR.Methods: The National Clinical Trial (NCT) database and PubMed were queried using a literature search strategy and reviewed by the authors.Results: Fourteen studies examining the application of PBT for AMD and nine studies examining the application of PBT for diabetic macular edema (DME) were extracted from 60 candidate publications.Discussion: Despite notable methodological differences between studies, PBT has been reported to treat certain DR and AMD patients. DR patients with center involving DME and VA ≥ 20/25 have demonstrated response to treatment. AMD patients at Age-Related Eye Disease Study Stages 2– 4 with VA ≥ 20/200 have also shown response to treatment. Results of major clinical trials are pending.Conclusion: PBT remains an emergent therapy with possible applications in DR and AMD. Further, high powered studies monitored by a neutral party with standard devices, treatment delivery and treatment timing are needed.Keywords: photobiomodulation therapy, age-related macular degeneration, diabetic macular edema, diabetic retinopathy
format	article
author	Muste JC Russell MW Singh RP
author_facet	Muste JC Russell MW Singh RP
author_sort	Muste JC
title	Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
title_short	Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
title_full	Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
title_fullStr	Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
title_full_unstemmed	Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review
title_sort	photobiomodulation therapy for age-related macular degeneration and diabetic retinopathy: a review
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/acfc425f5696496091f27e67a9a74076
work_keys_str_mv	AT mustejc photobiomodulationtherapyforagerelatedmaculardegenerationanddiabeticretinopathyareview AT russellmw photobiomodulationtherapyforagerelatedmaculardegenerationanddiabeticretinopathyareview AT singhrp photobiomodulationtherapyforagerelatedmaculardegenerationanddiabeticretinopathyareview
_version_	1718383592146468864

Photobiomodulation Therapy for Age-Related Macular Degeneration and Diabetic Retinopathy: A Review

Ejemplares similares