MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars

Introduction MRI guided focused ultrasound (MRgFUS) is a noninvasive technique for treating uterine fibroids. The presence of abdominal scars can limit the number of women eligible for the procedure, due to absorbance of beam energy. The goals of this study were to assess the number of women that fi...

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Autores principales:	Yael Inbar, Ronit Machtinger, Zohar Barnett-Itzhaki, Avishai Goldblatt, Eti Stoler, Jaron Rabinovici
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2021
Materias:	mrgfus fibroid laparotomy non-perfused volume (npv) abdominal scar(s) Medical technology R855-855.5
Acceso en línea:	https://doaj.org/article/acfe360876e34479a063336995572fb2
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spelling	oai:doaj.org-article:acfe360876e34479a063336995572fb22021-12-01T14:40:58ZMRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars0265-67361464-515710.1080/02656736.2021.2007302https://doaj.org/article/acfe360876e34479a063336995572fb22021-01-01T00:00:00Zhttp://dx.doi.org/10.1080/02656736.2021.2007302https://doaj.org/toc/0265-6736https://doaj.org/toc/1464-5157Introduction MRI guided focused ultrasound (MRgFUS) is a noninvasive technique for treating uterine fibroids. The presence of abdominal scars can limit the number of women eligible for the procedure, due to absorbance of beam energy. The goals of this study were to assess the number of women that fit the procedure and to compare outcomes among women with or without abdominal scars. Material and methods A prospective cohort study of all women that were interested in MRgFUS in a single University-Affiliated Hospital between November 2012 and December 2019. Rates of women that were referred to further screening, fulfilled selection criteria and underwent the procedure were compared between patients with or without abdominal scars. We evaluated the treatment parameters of the two groups and used linear regression model predict non-perfused volume (NPV) at the end of the process. Results Out of 701 patients, 21.8% were suitable for MRgFUS. Women with scars had significant lower NPV compared with women without scars (60% versus 82.4%, p = 0.021). No serious adverse events were reported in both groups. Linear regression models showed that fibroids' volume, stopping the treatment due to severe pain and the presence of abdominal scars had a statistically significantly negative effect on NPV (betas: −11.51, −6.96, and −6.29, p-values: <0.001, 0.003, and 0.007 respectively), while number of sonication had a statistically significantly positive effect on NPV (beta = 5.98, p = 0.011). Conclusion Regardless of strict inclusion criteria, MRgFUS treatment is less efficient among women with abdominal scars, although still feasible for those who are interested in noninvasive option.Yael InbarRonit MachtingerZohar Barnett-ItzhakiAvishai GoldblattEti StolerJaron RabinoviciTaylor & Francis Grouparticlemrgfusfibroidlaparotomynon-perfused volume (npv)abdominal scar(s)Medical technologyR855-855.5ENInternational Journal of Hyperthermia, Vol 38, Iss 1, Pp 1672-1676 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	mrgfus fibroid laparotomy non-perfused volume (npv) abdominal scar(s) Medical technology R855-855.5
spellingShingle	mrgfus fibroid laparotomy non-perfused volume (npv) abdominal scar(s) Medical technology R855-855.5 Yael Inbar Ronit Machtinger Zohar Barnett-Itzhaki Avishai Goldblatt Eti Stoler Jaron Rabinovici MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
description	Introduction MRI guided focused ultrasound (MRgFUS) is a noninvasive technique for treating uterine fibroids. The presence of abdominal scars can limit the number of women eligible for the procedure, due to absorbance of beam energy. The goals of this study were to assess the number of women that fit the procedure and to compare outcomes among women with or without abdominal scars. Material and methods A prospective cohort study of all women that were interested in MRgFUS in a single University-Affiliated Hospital between November 2012 and December 2019. Rates of women that were referred to further screening, fulfilled selection criteria and underwent the procedure were compared between patients with or without abdominal scars. We evaluated the treatment parameters of the two groups and used linear regression model predict non-perfused volume (NPV) at the end of the process. Results Out of 701 patients, 21.8% were suitable for MRgFUS. Women with scars had significant lower NPV compared with women without scars (60% versus 82.4%, p = 0.021). No serious adverse events were reported in both groups. Linear regression models showed that fibroids' volume, stopping the treatment due to severe pain and the presence of abdominal scars had a statistically significantly negative effect on NPV (betas: −11.51, −6.96, and −6.29, p-values: <0.001, 0.003, and 0.007 respectively), while number of sonication had a statistically significantly positive effect on NPV (beta = 5.98, p = 0.011). Conclusion Regardless of strict inclusion criteria, MRgFUS treatment is less efficient among women with abdominal scars, although still feasible for those who are interested in noninvasive option.
format	article
author	Yael Inbar Ronit Machtinger Zohar Barnett-Itzhaki Avishai Goldblatt Eti Stoler Jaron Rabinovici
author_facet	Yael Inbar Ronit Machtinger Zohar Barnett-Itzhaki Avishai Goldblatt Eti Stoler Jaron Rabinovici
author_sort	Yael Inbar
title	MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
title_short	MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
title_full	MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
title_fullStr	MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
title_full_unstemmed	MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars
title_sort	mri guided focused ultrasound (mrgfus) treatment for uterine fibroids among women with and without abdominal scars
publisher	Taylor & Francis Group
publishDate	2021
url	https://doaj.org/article/acfe360876e34479a063336995572fb2
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MRI guided focused ultrasound (MRgFUS) treatment for uterine fibroids among women with and without abdominal scars

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