Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways
Abstract Cancer-induced cachexia, characterized by muscle wasting, is a lethal metabolic syndrome with undefined etiology. Current consensus is that multiple factors contribute to cancer-induced muscle wasting, and therefore therapy requires combinational strategies. Here, we show that Toll-like rec...
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Autores principales: | Guohua Zhang, Zhelong Liu, Hui Ding, Hongyu Miao, Jose M. Garcia, Yi-Ping Li |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
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Acceso en línea: | https://doaj.org/article/ad02f855b6764ae9a516e85494dbc456 |
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