Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society

Abstract Systemic inflammation has been proposed as a physiological process linking socio-economic position (SEP) to health. We examined how SEP inequalities in inflammation –assessed using C-reactive protein (CRP) and fibrinogen– varied across the adult age span. Current (household income) and dist...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Apostolos Davillas, Michaela Benzeval, Meena Kumari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ad0b2794e70545ff927d6cf14cda5fef
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ad0b2794e70545ff927d6cf14cda5fef
record_format	dspace
spelling	oai:doaj.org-article:ad0b2794e70545ff927d6cf14cda5fef2021-12-02T15:05:59ZSocio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society10.1038/s41598-017-02888-62045-2322https://doaj.org/article/ad0b2794e70545ff927d6cf14cda5fef2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-02888-6https://doaj.org/toc/2045-2322Abstract Systemic inflammation has been proposed as a physiological process linking socio-economic position (SEP) to health. We examined how SEP inequalities in inflammation –assessed using C-reactive protein (CRP) and fibrinogen– varied across the adult age span. Current (household income) and distal (education) markers of SEP were used. Data from 7,943 participants (aged 25+) of Understanding Society (wave 2, 1/2010-3/2012) were employed. We found that SEP inequalities in inflammation followed heterogeneous patterns by age, which differed by the inflammatory marker examined rather than by SEP measures. SEP inequalities in CRP emerged in 30s, increased up to mid-50s or early 60 s when they peaked and then decreased with age. SEP inequalities in fibrinogen decreased with age. Body mass index (BMI), smoking, physical activity and healthy diet explained part, but not all, of the SEP inequalities in inflammation; in general, BMI exerted the largest attenuation. Cumulative advantage theories and those considering age as a leveler for the accumulation of health and economic advantages across the life-span should be dynamically integrated to better understand the observed heterogeneity in SEP differences in health across the lifespan. The attenuating roles of health-related lifestyle indicators suggest that targeting health promotion policies may help reduce SEP inequalities in health.Apostolos DavillasMichaela BenzevalMeena KumariNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Apostolos Davillas Michaela Benzeval Meena Kumari Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
description	Abstract Systemic inflammation has been proposed as a physiological process linking socio-economic position (SEP) to health. We examined how SEP inequalities in inflammation –assessed using C-reactive protein (CRP) and fibrinogen– varied across the adult age span. Current (household income) and distal (education) markers of SEP were used. Data from 7,943 participants (aged 25+) of Understanding Society (wave 2, 1/2010-3/2012) were employed. We found that SEP inequalities in inflammation followed heterogeneous patterns by age, which differed by the inflammatory marker examined rather than by SEP measures. SEP inequalities in CRP emerged in 30s, increased up to mid-50s or early 60 s when they peaked and then decreased with age. SEP inequalities in fibrinogen decreased with age. Body mass index (BMI), smoking, physical activity and healthy diet explained part, but not all, of the SEP inequalities in inflammation; in general, BMI exerted the largest attenuation. Cumulative advantage theories and those considering age as a leveler for the accumulation of health and economic advantages across the life-span should be dynamically integrated to better understand the observed heterogeneity in SEP differences in health across the lifespan. The attenuating roles of health-related lifestyle indicators suggest that targeting health promotion policies may help reduce SEP inequalities in health.
format	article
author	Apostolos Davillas Michaela Benzeval Meena Kumari
author_facet	Apostolos Davillas Michaela Benzeval Meena Kumari
author_sort	Apostolos Davillas
title	Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
title_short	Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
title_full	Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
title_fullStr	Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
title_full_unstemmed	Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society
title_sort	socio-economic inequalities in c-reactive protein and fibrinogen across the adult age span: findings from understanding society
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ad0b2794e70545ff927d6cf14cda5fef
work_keys_str_mv	AT apostolosdavillas socioeconomicinequalitiesincreactiveproteinandfibrinogenacrosstheadultagespanfindingsfromunderstandingsociety AT michaelabenzeval socioeconomicinequalitiesincreactiveproteinandfibrinogenacrosstheadultagespanfindingsfromunderstandingsociety AT meenakumari socioeconomicinequalitiesincreactiveproteinandfibrinogenacrosstheadultagespanfindingsfromunderstandingsociety
_version_	1718388664596168704

Socio-economic inequalities in C-reactive protein and fibrinogen across the adult age span: Findings from Understanding Society

Ejemplares similares