LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity

Objectives. Increased metabolic and cardiovascular morbidity has been reported in multiple sclerosis (MS) patients. Previously, we have found decreased insulin sensitivity and hyperinsulinemia in a group of newly diagnosed MS patients. We hypothesize that these features may be associated with an alt...

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Autores principales: Radikova Zofia, Penesova Adela, Vlcek Miroslav, Havranova Andrea, Sivakova Monika, Siarnik Pavel, Zitnanova Ingrid, Imrich Richard, Kollar Branislav, Turcani Peter
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Lenguaje:EN
Publicado: Sciendo 2018
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Acceso en línea:https://doaj.org/article/ad0c1315ca164bd2a8de114040a5fe5b
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spelling oai:doaj.org-article:ad0c1315ca164bd2a8de114040a5fe5b2021-12-02T16:40:25ZLDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity1336-032910.2478/enr-2018-0017https://doaj.org/article/ad0c1315ca164bd2a8de114040a5fe5b2018-07-01T00:00:00Zhttps://doi.org/10.2478/enr-2018-0017https://doaj.org/toc/1336-0329Objectives. Increased metabolic and cardiovascular morbidity has been reported in multiple sclerosis (MS) patients. Previously, we have found decreased insulin sensitivity and hyperinsulinemia in a group of newly diagnosed MS patients. We hypothesize that these features may be associated with an altered lipid profile and low, intermediate, or high density lipoprotein (LDL, IDL, HDL) subclasses accelerating atherosclerosis and thus contributing to the cardiovascular risk increase in these patients.Radikova ZofiaPenesova AdelaVlcek MiroslavHavranova AndreaSivakova MonikaSiarnik PavelZitnanova IngridImrich RichardKollar BranislavTurcani PeterSciendoarticlemultiple sclerosisinsulin resistancelipoproteinscholesterolDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 52, Iss 3, Pp 139-145 (2018)
institution DOAJ
collection DOAJ
language EN
topic multiple sclerosis
insulin resistance
lipoproteins
cholesterol
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle multiple sclerosis
insulin resistance
lipoproteins
cholesterol
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Radikova Zofia
Penesova Adela
Vlcek Miroslav
Havranova Andrea
Sivakova Monika
Siarnik Pavel
Zitnanova Ingrid
Imrich Richard
Kollar Branislav
Turcani Peter
LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
description Objectives. Increased metabolic and cardiovascular morbidity has been reported in multiple sclerosis (MS) patients. Previously, we have found decreased insulin sensitivity and hyperinsulinemia in a group of newly diagnosed MS patients. We hypothesize that these features may be associated with an altered lipid profile and low, intermediate, or high density lipoprotein (LDL, IDL, HDL) subclasses accelerating atherosclerosis and thus contributing to the cardiovascular risk increase in these patients.
format article
author Radikova Zofia
Penesova Adela
Vlcek Miroslav
Havranova Andrea
Sivakova Monika
Siarnik Pavel
Zitnanova Ingrid
Imrich Richard
Kollar Branislav
Turcani Peter
author_facet Radikova Zofia
Penesova Adela
Vlcek Miroslav
Havranova Andrea
Sivakova Monika
Siarnik Pavel
Zitnanova Ingrid
Imrich Richard
Kollar Branislav
Turcani Peter
author_sort Radikova Zofia
title LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
title_short LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
title_full LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
title_fullStr LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
title_full_unstemmed LDL and HDL lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
title_sort ldl and hdl lipoprotein subfractions in multiple sclerosis patients with decreased insulin sensitivity
publisher Sciendo
publishDate 2018
url https://doaj.org/article/ad0c1315ca164bd2a8de114040a5fe5b
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