Identification of 4-Amino-Thieno[2,3-<italic toggle="yes">d</italic>]Pyrimidines as QcrB Inhibitors in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Identification of 4-Amino-Thieno[2,3-<italic toggle="yes">d</italic>]Pyrimidines as QcrB Inhibitors in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Antibiotic resistance is a global crisis that threatens our ability to treat bacterial infections, such as tuberculosis, caused by Mycobacterium tuberculosis. Of the 10 million cases of tuberculosis in 2017, approximately 19% of new cases and 43% of previously treated cases were caused by s...

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Autores principales: Gregory A. Harrison, Anne E. Mayer Bridwell, Megh Singh, Keshav Jayaraman, Leslie A. Weiss, Rachel L. Kinsella, Janessa S. Aneke, Kelly Flentie, Miranda E. Schene, Margaret Gaggioli, Samantha D. Solomon, Scott A. Wildman, Marvin J. Meyers, Christina L. Stallings
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
CydAB
Mycobacterium tuberculosis
QcrB
antibiotic
cytochrome
drug discovery
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/ad17de60be774608b65761e5e9fd4004
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