Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives

Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biol...

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Autores principales: Gang Wang, Xiaodong Xin, Zehua Wang, Gang Lu, Yudao Ma, Lei Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc
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Sumario:Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biologically active molecules.