Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biol...
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Nature Portfolio
2019
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oai:doaj.org-article:ad2a5fea76d243c68b811172191d20dc2021-12-02T15:35:49ZCatalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives10.1038/s41467-019-08473-x2041-1723https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08473-xhttps://doaj.org/toc/2041-1723Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biologically active molecules.Gang WangXiaodong XinZehua WangGang LuYudao MaLei LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019) |
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Science Q Gang Wang Xiaodong Xin Zehua Wang Gang Lu Yudao Ma Lei Liu Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
description |
Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biologically active molecules. |
format |
article |
author |
Gang Wang Xiaodong Xin Zehua Wang Gang Lu Yudao Ma Lei Liu |
author_facet |
Gang Wang Xiaodong Xin Zehua Wang Gang Lu Yudao Ma Lei Liu |
author_sort |
Gang Wang |
title |
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
title_short |
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
title_full |
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
title_fullStr |
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
title_full_unstemmed |
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
title_sort |
catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc |
work_keys_str_mv |
AT gangwang catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives AT xiaodongxin catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives AT zehuawang catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives AT ganglu catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives AT yudaoma catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives AT leiliu catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives |
_version_ |
1718386432595197952 |