Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives

Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biol...

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Auteurs principaux: Gang Wang, Xiaodong Xin, Zehua Wang, Gang Lu, Yudao Ma, Lei Liu
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc
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spelling oai:doaj.org-article:ad2a5fea76d243c68b811172191d20dc2021-12-02T15:35:49ZCatalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives10.1038/s41467-019-08473-x2041-1723https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08473-xhttps://doaj.org/toc/2041-1723Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biologically active molecules.Gang WangXiaodong XinZehua WangGang LuYudao MaLei LiuNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gang Wang
Xiaodong Xin
Zehua Wang
Gang Lu
Yudao Ma
Lei Liu
Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
description Cross-dehydrogenative coupling (CDC) is a powerful method for C-C bond formation however the enantioselective variant is underdeveloped. Here, the authors show a formal enantioselective CDC method involving unactivated ethers and carboxylic acid derivatives allowing for the rapid preparation of biologically active molecules.
format article
author Gang Wang
Xiaodong Xin
Zehua Wang
Gang Lu
Yudao Ma
Lei Liu
author_facet Gang Wang
Xiaodong Xin
Zehua Wang
Gang Lu
Yudao Ma
Lei Liu
author_sort Gang Wang
title Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
title_short Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
title_full Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
title_fullStr Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
title_full_unstemmed Catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
title_sort catalytic enantioselective oxidative coupling of saturated ethers with carboxylic acid derivatives
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/ad2a5fea76d243c68b811172191d20dc
work_keys_str_mv AT gangwang catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
AT xiaodongxin catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
AT zehuawang catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
AT ganglu catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
AT yudaoma catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
AT leiliu catalyticenantioselectiveoxidativecouplingofsaturatedetherswithcarboxylicacidderivatives
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