The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al. show that cells expressing VIP or its receptor VPAC2 together determine these emergent prop...

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Autores principales: Andrew P. Patton, Mathew D. Edwards, Nicola J. Smyllie, Ryan Hamnett, Johanna E. Chesham, Marco Brancaccio, Elizabeth S. Maywood, Michael H. Hastings
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ad309a8df6944f3b8e02686e390f2b1d
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spelling oai:doaj.org-article:ad309a8df6944f3b8e02686e390f2b1d2021-12-02T15:23:19ZThe VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit10.1038/s41467-020-17110-x2041-1723https://doaj.org/article/ad309a8df6944f3b8e02686e390f2b1d2020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17110-xhttps://doaj.org/toc/2041-1723Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al. show that cells expressing VIP or its receptor VPAC2 together determine these emergent properties of the SCN.Andrew P. PattonMathew D. EdwardsNicola J. SmyllieRyan HamnettJohanna E. CheshamMarco BrancaccioElizabeth S. MaywoodMichael H. HastingsNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrew P. Patton
Mathew D. Edwards
Nicola J. Smyllie
Ryan Hamnett
Johanna E. Chesham
Marco Brancaccio
Elizabeth S. Maywood
Michael H. Hastings
The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
description Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al. show that cells expressing VIP or its receptor VPAC2 together determine these emergent properties of the SCN.
format article
author Andrew P. Patton
Mathew D. Edwards
Nicola J. Smyllie
Ryan Hamnett
Johanna E. Chesham
Marco Brancaccio
Elizabeth S. Maywood
Michael H. Hastings
author_facet Andrew P. Patton
Mathew D. Edwards
Nicola J. Smyllie
Ryan Hamnett
Johanna E. Chesham
Marco Brancaccio
Elizabeth S. Maywood
Michael H. Hastings
author_sort Andrew P. Patton
title The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
title_short The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
title_full The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
title_fullStr The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
title_full_unstemmed The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
title_sort vip-vpac2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/ad309a8df6944f3b8e02686e390f2b1d
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