The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

Circadian activity modulation in the suprachiasmatic nucleus (SCN) is a network-level emergent property that requires neuropeptide VIP signaling, yet the precise cellular mechanisms are unknown. Patton et al. show that cells expressing VIP or its receptor VPAC2 together determine these emergent prop...

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Autores principales: Andrew P. Patton, Mathew D. Edwards, Nicola J. Smyllie, Ryan Hamnett, Johanna E. Chesham, Marco Brancaccio, Elizabeth S. Maywood, Michael H. Hastings
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/ad309a8df6944f3b8e02686e390f2b1d
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