The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair

Abstract EXD2 is a recently identified exonuclease that has been implicated in nuclear double-strand break repair. Given our long standing interest in mitochondrial DNA maintenance and indications that EXD2 could also be a mitochondrial protein we sought to determine its cellular localization and po...

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Autores principales: Fenna Hensen, Amandine Moretton, Selma van Esveld, Géraldine Farge, Johannes N. Spelbrink
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/ad38501bd0364dfbada911fe5c79d899
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