Conserved molecular signatures in the spike protein provide evidence indicating the origin of SARS-CoV-2 and a Pangolin-CoV (MP789) by recombination(s) between specific lineages of Sarbecoviruses
Both SARS-CoV-2 and SARS coronaviruses (CoVs) are members of the subgenus Sarbecovirus. To understand the origin of SARS-CoV-2, sequences for the spike and nucleocapsid proteins from sarbecoviruses were analyzed to identify molecular markers consisting of conserved inserts or deletions (termed CSIs)...
Guardado en:
Autores principales: | Bijendra Khadka, Radhey S. Gupta |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
PeerJ Inc.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ad3d83601f764e008b21595a0da3068b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Can the SARS-CoV-2 Spike Protein Bind Integrins Independent of the RGD Sequence?
por: Christopher A. Beaudoin, et al.
Publicado: (2021) -
Decline of Humoral Responses against SARS-CoV-2 Spike in Convalescent Individuals
por: Guillaume Beaudoin-Bussières, et al.
Publicado: (2020) -
D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Virus Titer via Enhanced Furin-Mediated Spike Cleavage
por: Ya-Wen Cheng, et al.
Publicado: (2021) -
SARS-CoV-2 spike protein: Site-specific breakpoints for the development of COVID-19 vaccines
por: Palaniyandi Velusamy, et al.
Publicado: (2021) -
Introduction of Two Prolines and Removal of the Polybasic Cleavage Site Lead to Higher Efficacy of a Recombinant Spike-Based SARS-CoV-2 Vaccine in the Mouse Model
por: Fatima Amanat, et al.
Publicado: (2021)