Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT

Background: Acute otitis media is a painful infection of the middle ear that is commonly seen in children. In some children, the eardrum spontaneously bursts, discharging visible pus (otorrhoea) into the outer ear. Objective: To compare the clinical effectiveness of immediate topical antibiotics or...

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Main Authors:	Alastair D Hay, Michael V Moore, Jodi Taylor, Nicholas Turner, Sian Noble, Christie Cabral, Jeremy Horwood, Vibhore Prasad, Kathryn Curtis, Brendan Delaney, Roger Damoiseaux, Jesús Domínguez, Archana Tapuria, Sue Harris, Paul Little, Andrew Lovering, Richard Morris, Kate Rowley, Annie Sadoo, Anne Schilder, Roderick Venekamp, Scott Wilkes, Vasa Curcin
Format:	article
Language:	EN
Published:	NIHR Journals Library 2021
Subjects:	acute otitis media primary care antibiotics paediatrics Medical technology R855-855.5
Online Access:	https://doaj.org/article/ad42f86dfc47479a80aaa18c523c7209
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Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT

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