Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer
A thermophoretic aptasensor can be used to profile cancer-associated proteins of extracellular vesicles (EVs) in patients’ plasma. Here, the authors use this technique to develop an EV-signature able to discriminate metastatic breast cancer, monitor treatment response, and predict patients’ progress...
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Nature Portfolio
2021
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oai:doaj.org-article:ad4f67eb76a945bbab6cae162e3f55be2021-12-02T14:29:13ZProtein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer10.1038/s41467-021-22913-72041-1723https://doaj.org/article/ad4f67eb76a945bbab6cae162e3f55be2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22913-7https://doaj.org/toc/2041-1723A thermophoretic aptasensor can be used to profile cancer-associated proteins of extracellular vesicles (EVs) in patients’ plasma. Here, the authors use this technique to develop an EV-signature able to discriminate metastatic breast cancer, monitor treatment response, and predict patients’ progression-free survival.Fei TianShaohua ZhangChao LiuZiwei HanYuan LiuJinqi DengYike LiXia WuLili CaiLili QinQinghua ChenYang YuanYi LiuYulong CongBaoquan DingZefei JiangJiashu SunNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
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EN |
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Science Q Fei Tian Shaohua Zhang Chao Liu Ziwei Han Yuan Liu Jinqi Deng Yike Li Xia Wu Lili Cai Lili Qin Qinghua Chen Yang Yuan Yi Liu Yulong Cong Baoquan Ding Zefei Jiang Jiashu Sun Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
description |
A thermophoretic aptasensor can be used to profile cancer-associated proteins of extracellular vesicles (EVs) in patients’ plasma. Here, the authors use this technique to develop an EV-signature able to discriminate metastatic breast cancer, monitor treatment response, and predict patients’ progression-free survival. |
format |
article |
author |
Fei Tian Shaohua Zhang Chao Liu Ziwei Han Yuan Liu Jinqi Deng Yike Li Xia Wu Lili Cai Lili Qin Qinghua Chen Yang Yuan Yi Liu Yulong Cong Baoquan Ding Zefei Jiang Jiashu Sun |
author_facet |
Fei Tian Shaohua Zhang Chao Liu Ziwei Han Yuan Liu Jinqi Deng Yike Li Xia Wu Lili Cai Lili Qin Qinghua Chen Yang Yuan Yi Liu Yulong Cong Baoquan Ding Zefei Jiang Jiashu Sun |
author_sort |
Fei Tian |
title |
Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
title_short |
Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
title_full |
Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
title_fullStr |
Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
title_full_unstemmed |
Protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
title_sort |
protein analysis of extracellular vesicles to monitor and predict therapeutic response in metastatic breast cancer |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/ad4f67eb76a945bbab6cae162e3f55be |
work_keys_str_mv |
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