Thermosensitive hydrogel for in situ-controlled methotrexate delivery

MTX is loaded and released in a controlled manner over 14 h, under physiological conditions, from an amphiphilic triblock copolymer with a sol–gel phase change at 36.5°C.

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Autores principales: Carrillo-Castillo Teresa Darlen, Luna-Velasco Antonia, Zaragoza-Contreras Erasto Armando, Castro-Carmona Javier Servando
Formato: article
Lenguaje:EN
Publicado: De Gruyter 2021
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Acceso en línea:https://doaj.org/article/ad683dc6eccc4f518283534a006cef77
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spelling oai:doaj.org-article:ad683dc6eccc4f518283534a006cef772021-12-05T14:10:48ZThermosensitive hydrogel for in situ-controlled methotrexate delivery1618-722910.1515/epoly-2021-0085https://doaj.org/article/ad683dc6eccc4f518283534a006cef772021-11-01T00:00:00Zhttps://doi.org/10.1515/epoly-2021-0085https://doaj.org/toc/1618-7229MTX is loaded and released in a controlled manner over 14 h, under physiological conditions, from an amphiphilic triblock copolymer with a sol–gel phase change at 36.5°C.Carrillo-Castillo Teresa DarlenLuna-Velasco AntoniaZaragoza-Contreras Erasto ArmandoCastro-Carmona Javier ServandoDe Gruyterarticlecopolymercytotoxicitydrug deliveryhydrogelmethotrexatePolymers and polymer manufactureTP1080-1185ENe-Polymers, Vol 21, Iss 1, Pp 910-920 (2021)
institution DOAJ
collection DOAJ
language EN
topic copolymer
cytotoxicity
drug delivery
hydrogel
methotrexate
Polymers and polymer manufacture
TP1080-1185
spellingShingle copolymer
cytotoxicity
drug delivery
hydrogel
methotrexate
Polymers and polymer manufacture
TP1080-1185
Carrillo-Castillo Teresa Darlen
Luna-Velasco Antonia
Zaragoza-Contreras Erasto Armando
Castro-Carmona Javier Servando
Thermosensitive hydrogel for in situ-controlled methotrexate delivery
description MTX is loaded and released in a controlled manner over 14 h, under physiological conditions, from an amphiphilic triblock copolymer with a sol–gel phase change at 36.5°C.
format article
author Carrillo-Castillo Teresa Darlen
Luna-Velasco Antonia
Zaragoza-Contreras Erasto Armando
Castro-Carmona Javier Servando
author_facet Carrillo-Castillo Teresa Darlen
Luna-Velasco Antonia
Zaragoza-Contreras Erasto Armando
Castro-Carmona Javier Servando
author_sort Carrillo-Castillo Teresa Darlen
title Thermosensitive hydrogel for in situ-controlled methotrexate delivery
title_short Thermosensitive hydrogel for in situ-controlled methotrexate delivery
title_full Thermosensitive hydrogel for in situ-controlled methotrexate delivery
title_fullStr Thermosensitive hydrogel for in situ-controlled methotrexate delivery
title_full_unstemmed Thermosensitive hydrogel for in situ-controlled methotrexate delivery
title_sort thermosensitive hydrogel for in situ-controlled methotrexate delivery
publisher De Gruyter
publishDate 2021
url https://doaj.org/article/ad683dc6eccc4f518283534a006cef77
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AT lunavelascoantonia thermosensitivehydrogelforinsitucontrolledmethotrexatedelivery
AT zaragozacontreraserastoarmando thermosensitivehydrogelforinsitucontrolledmethotrexatedelivery
AT castrocarmonajavierservando thermosensitivehydrogelforinsitucontrolledmethotrexatedelivery
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