GRP78/BiP determines senescence evasion cell fate after cisplatin-based chemotherapy

Abstract Cisplatin (CDDP) induces senescence characterized by senescence-associated secretory phenotypes (SASP) and the unfolded protein response (UPR). In this study, we investigated the proteins related to the UPR during the senescence cell fate. Strikingly, we found that one of the critical ER-re...

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Bibliographic Details
Main Authors: Zin Zin Ei, Kanuengnit Choochuay, Alisa Tubsuwan, Decha Pinkaew, Maneewan Suksomtip, Chanida Vinayanuwattikun, Pithi Chanvorachote, Preedakorn Chunhacha
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/ad6d1a96e493418c8a33cafca4d13c0c
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