Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit

DNA methylation patterns are inherited over many generations in plants. Here, Williams and Gehring show that the 5-methylcytosine DNA glycosylase ROS1 functions as part of a methylation-sensitive circuit that ensures long-term epigenetic fidelity in Arabidopsis.

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Autores principales:	Ben P. Williams, Mary Gehring
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ad6d7eb45f434846a9749db5a392c023
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spelling	oai:doaj.org-article:ad6d7eb45f434846a9749db5a392c0232021-12-02T14:41:11ZStable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit10.1038/s41467-017-02219-32041-1723https://doaj.org/article/ad6d7eb45f434846a9749db5a392c0232017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02219-3https://doaj.org/toc/2041-1723DNA methylation patterns are inherited over many generations in plants. Here, Williams and Gehring show that the 5-methylcytosine DNA glycosylase ROS1 functions as part of a methylation-sensitive circuit that ensures long-term epigenetic fidelity in Arabidopsis.Ben P. WilliamsMary GehringNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ben P. Williams Mary Gehring Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
description	DNA methylation patterns are inherited over many generations in plants. Here, Williams and Gehring show that the 5-methylcytosine DNA glycosylase ROS1 functions as part of a methylation-sensitive circuit that ensures long-term epigenetic fidelity in Arabidopsis.
format	article
author	Ben P. Williams Mary Gehring
author_facet	Ben P. Williams Mary Gehring
author_sort	Ben P. Williams
title	Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
title_short	Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
title_full	Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
title_fullStr	Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
title_full_unstemmed	Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit
title_sort	stable transgenerational epigenetic inheritance requires a dna methylation-sensing circuit
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/ad6d7eb45f434846a9749db5a392c023
work_keys_str_mv	AT benpwilliams stabletransgenerationalepigeneticinheritancerequiresadnamethylationsensingcircuit AT marygehring stabletransgenerationalepigeneticinheritancerequiresadnamethylationsensingcircuit
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Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit

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