CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS
In view of abundance of autoimmune diseases of thyroid, gland, Graves' disease in particular, the role of immune regulation and the possibility of controlling it by estimating the function of regulatory T-limphocytes are important questions today. Available for practical estimation of T- and B-...
Guardado en:
| Autores principales: | , |
|---|---|
| Formato: | article |
| Lenguaje: | RU |
| Publicado: |
Scientific Сentre for Family Health and Human Reproduction Problems
2012
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/ad71fdaed86c40ed9695c9de15122740 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:ad71fdaed86c40ed9695c9de15122740 |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:ad71fdaed86c40ed9695c9de151227402021-11-23T06:14:20ZCYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS2541-94202587-9596https://doaj.org/article/ad71fdaed86c40ed9695c9de151227402012-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/935https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596In view of abundance of autoimmune diseases of thyroid, gland, Graves' disease in particular, the role of immune regulation and the possibility of controlling it by estimating the function of regulatory T-limphocytes are important questions today. Available for practical estimation of T- and B-lymphocytes tolerance disorder in GBD are serum, levels of Th1-and Th2-marker cytokines. Experimental exogenous thyreotoxicosis in Wistar rats showed significant increase in serum Il-1β, IFN-γ and Il-10 depending on the increase of thyroid hormones, as well as significant changes in correlation between pro-and anti-inflammatory cytokines with the shift towards Th1-marker cytokines in supernatant thyroid glands of the animals with thyreotoxicosis.V. V. ZdorE. V. MarkelovaScientific Сentre for Family Health and Human Reproduction ProblemsarticleexperimentratsthyreotoxicosiscytokinesScienceQRUActa Biomedica Scientifica, Vol 0, Iss 3(2), Pp 280-283 (2012) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
RU |
| topic |
experiment rats thyreotoxicosis cytokines Science Q |
| spellingShingle |
experiment rats thyreotoxicosis cytokines Science Q V. V. Zdor E. V. Markelova CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| description |
In view of abundance of autoimmune diseases of thyroid, gland, Graves' disease in particular, the role of immune regulation and the possibility of controlling it by estimating the function of regulatory T-limphocytes are important questions today. Available for practical estimation of T- and B-lymphocytes tolerance disorder in GBD are serum, levels of Th1-and Th2-marker cytokines. Experimental exogenous thyreotoxicosis in Wistar rats showed significant increase in serum Il-1β, IFN-γ and Il-10 depending on the increase of thyroid hormones, as well as significant changes in correlation between pro-and anti-inflammatory cytokines with the shift towards Th1-marker cytokines in supernatant thyroid glands of the animals with thyreotoxicosis. |
| format |
article |
| author |
V. V. Zdor E. V. Markelova |
| author_facet |
V. V. Zdor E. V. Markelova |
| author_sort |
V. V. Zdor |
| title |
CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| title_short |
CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| title_full |
CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| title_fullStr |
CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| title_full_unstemmed |
CYTOKINE PROFILE IN WISTAR RATS WITH EXPERIMENTAL THYREOTOXICOSIS |
| title_sort |
cytokine profile in wistar rats with experimental thyreotoxicosis |
| publisher |
Scientific Сentre for Family Health and Human Reproduction Problems |
| publishDate |
2012 |
| url |
https://doaj.org/article/ad71fdaed86c40ed9695c9de15122740 |
| work_keys_str_mv |
AT vvzdor cytokineprofileinwistarratswithexperimentalthyreotoxicosis AT evmarkelova cytokineprofileinwistarratswithexperimentalthyreotoxicosis |
| _version_ |
1718417271861280768 |