Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle.

Paradoxical increase in TAG and DAG content parallel the insulin sensitizing effect of unilateral DGAT1 overexpression in rat skeletal muscle.

<h4>Background</h4>The involvement of muscle triacylglycerol (TAG) storage in the onset of insulin resistance is questioned and the attention has shifted towards inhibition of insulin signalling by the lipid intermediate diacylglycerol (DAG). The enzyme 1,2-acylCoA:diacylglyceroltransfer...

Full description

Saved in:
Bibliographic Details
Main Authors: Silvie Timmers, Johan de Vogel-van den Bosch, Matthijs K C Hesselink, Denis van Beurden, Gert Schaart, Maria Joao Ferraz, Mario Losen, Pilar Martinez-Martinez, Marc H De Baets, Johannes M F G Aerts, Patrick Schrauwen
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/ad75f3a726a74f138354472eda7e5d3b
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items