Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate.
The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us...
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2013
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oai:doaj.org-article:ad7dc7b64fbc41bd87b9096edfe82feb2021-11-18T05:37:45ZReflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate.1544-91731545-788510.1371/journal.pbio.1001699https://doaj.org/article/ad7dc7b64fbc41bd87b9096edfe82feb2013-11-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24223516/pdf/?tool=EBIhttps://doaj.org/toc/1544-9173https://doaj.org/toc/1545-7885The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us about potential benefits and harms, particularly in the context of health care policy. The scale and pace of adoption of this powerful new technology should be driven by clinical need, clinical evidence, and a commitment to put patients at the centre of health care policy.Timothy CaulfieldJim EvansAmy McGuireChristopher McCabeTania BubelaRobert Cook-DeeganJennifer FishmanStuart HogarthFiona A MillerVardit RavitskyBarbara BieseckerPascal BorryMildred K ChoJune C CarrollHolly EtchegaryYann JolyKazuto KatoSandra Soo-Jin LeeKaren RothenbergPamela SankarMichael J SzegoPilar OssorioDaryl PullmanFrancois RousseauWendy J UngarBrenda WilsonPublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Biology, Vol 11, Iss 11, p e1001699 (2013) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Biology (General) QH301-705.5 |
| spellingShingle |
Biology (General) QH301-705.5 Timothy Caulfield Jim Evans Amy McGuire Christopher McCabe Tania Bubela Robert Cook-Deegan Jennifer Fishman Stuart Hogarth Fiona A Miller Vardit Ravitsky Barbara Biesecker Pascal Borry Mildred K Cho June C Carroll Holly Etchegary Yann Joly Kazuto Kato Sandra Soo-Jin Lee Karen Rothenberg Pamela Sankar Michael J Szego Pilar Ossorio Daryl Pullman Francois Rousseau Wendy J Ungar Brenda Wilson Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| description |
The cost of whole genome sequencing is dropping rapidly. There has been a great deal of enthusiasm about the potential for this technological advance to transform clinical care. Given the interest and significant investment in genomics, this seems an ideal time to consider what the evidence tells us about potential benefits and harms, particularly in the context of health care policy. The scale and pace of adoption of this powerful new technology should be driven by clinical need, clinical evidence, and a commitment to put patients at the centre of health care policy. |
| format |
article |
| author |
Timothy Caulfield Jim Evans Amy McGuire Christopher McCabe Tania Bubela Robert Cook-Deegan Jennifer Fishman Stuart Hogarth Fiona A Miller Vardit Ravitsky Barbara Biesecker Pascal Borry Mildred K Cho June C Carroll Holly Etchegary Yann Joly Kazuto Kato Sandra Soo-Jin Lee Karen Rothenberg Pamela Sankar Michael J Szego Pilar Ossorio Daryl Pullman Francois Rousseau Wendy J Ungar Brenda Wilson |
| author_facet |
Timothy Caulfield Jim Evans Amy McGuire Christopher McCabe Tania Bubela Robert Cook-Deegan Jennifer Fishman Stuart Hogarth Fiona A Miller Vardit Ravitsky Barbara Biesecker Pascal Borry Mildred K Cho June C Carroll Holly Etchegary Yann Joly Kazuto Kato Sandra Soo-Jin Lee Karen Rothenberg Pamela Sankar Michael J Szego Pilar Ossorio Daryl Pullman Francois Rousseau Wendy J Ungar Brenda Wilson |
| author_sort |
Timothy Caulfield |
| title |
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| title_short |
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| title_full |
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| title_fullStr |
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| title_full_unstemmed |
Reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| title_sort |
reflections on the cost of "low-cost" whole genome sequencing: framing the health policy debate. |
| publisher |
Public Library of Science (PLoS) |
| publishDate |
2013 |
| url |
https://doaj.org/article/ad7dc7b64fbc41bd87b9096edfe82feb |
| work_keys_str_mv |
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1718424871845756928 |