Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation

Abstract Hypoxemia can occur during endoscopic retrograde cholangiography (ERCP) and it is difficult to achieve adequate ventilation with the prone position. High-flow nasal oxygen (HFNO) has been recommended to be more effectively help ventilation than conventional low flow oxygen. The aim of this...

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Autores principales:	Boram Cha, Man-Jong Lee, Jin-Seok Park, Seok Jeong, Don Haeng Lee, Tae Gyu Park
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ad7e8bb8d62442368b665dcf42ec1619
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spelling	oai:doaj.org-article:ad7e8bb8d62442368b665dcf42ec16192021-12-02T15:23:10ZClinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation10.1038/s41598-020-79798-72045-2322https://doaj.org/article/ad7e8bb8d62442368b665dcf42ec16192021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79798-7https://doaj.org/toc/2045-2322Abstract Hypoxemia can occur during endoscopic retrograde cholangiography (ERCP) and it is difficult to achieve adequate ventilation with the prone position. High-flow nasal oxygen (HFNO) has been recommended to be more effectively help ventilation than conventional low flow oxygen. The aim of this study was to evaluate the effect of HFNO during sedated ERCP and to identify predictors of desaturation during ERCP. The investigated variables were age, gender, American Society of Anesthesiologists classes (ASA), duration of exam, and sedative used for midazolam or/and propofol of 262 patients with sedated ERCP. The differences between categorical and continuous variables were analyzed using the Student’s t test and the chi-square test. Desaturation (SpO2 ≤ 90%) occurred in 9(3.4%) patients among 262 patients during sedated ERCP. The variables found to predict desaturation were older age (p < 0.01), higher sedation dose for midazolam or propofol (p < 0.01), and use of midazolam (p < 0.01). Desaturation rate was lower during sedated ERCP with HFNO compared to the preliminary study with conventional low flow nasal oxygen. Patients with older age, higher sedation dose, or the use of midazolam might require close monitoring for desaturation and hypoventilation by nursing staff. The study shows the use of high-flow nasal oxygen reduces the incidence of desaturation during ERCP.Boram ChaMan-Jong LeeJin-Seok ParkSeok JeongDon Haeng LeeTae Gyu ParkNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Boram Cha Man-Jong Lee Jin-Seok Park Seok Jeong Don Haeng Lee Tae Gyu Park Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
description	Abstract Hypoxemia can occur during endoscopic retrograde cholangiography (ERCP) and it is difficult to achieve adequate ventilation with the prone position. High-flow nasal oxygen (HFNO) has been recommended to be more effectively help ventilation than conventional low flow oxygen. The aim of this study was to evaluate the effect of HFNO during sedated ERCP and to identify predictors of desaturation during ERCP. The investigated variables were age, gender, American Society of Anesthesiologists classes (ASA), duration of exam, and sedative used for midazolam or/and propofol of 262 patients with sedated ERCP. The differences between categorical and continuous variables were analyzed using the Student’s t test and the chi-square test. Desaturation (SpO2 ≤ 90%) occurred in 9(3.4%) patients among 262 patients during sedated ERCP. The variables found to predict desaturation were older age (p < 0.01), higher sedation dose for midazolam or propofol (p < 0.01), and use of midazolam (p < 0.01). Desaturation rate was lower during sedated ERCP with HFNO compared to the preliminary study with conventional low flow nasal oxygen. Patients with older age, higher sedation dose, or the use of midazolam might require close monitoring for desaturation and hypoventilation by nursing staff. The study shows the use of high-flow nasal oxygen reduces the incidence of desaturation during ERCP.
format	article
author	Boram Cha Man-Jong Lee Jin-Seok Park Seok Jeong Don Haeng Lee Tae Gyu Park
author_facet	Boram Cha Man-Jong Lee Jin-Seok Park Seok Jeong Don Haeng Lee Tae Gyu Park
author_sort	Boram Cha
title	Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
title_short	Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
title_full	Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
title_fullStr	Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
title_full_unstemmed	Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation
title_sort	clinical efficacy of high-flow nasal oxygen in patients undergoing ercp under sedation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ad7e8bb8d62442368b665dcf42ec1619
work_keys_str_mv	AT boramcha clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation AT manjonglee clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation AT jinseokpark clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation AT seokjeong clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation AT donhaenglee clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation AT taegyupark clinicalefficacyofhighflownasaloxygeninpatientsundergoingercpundersedation
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Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation

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