Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity

Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity

Abstract MCM7, a subunit of mini-chromosome maintenance proteins (MCM) complex, plays an important role in initiating DNA replication during the G1 phase and extending DNA strands during the S phase. Here, we demonstrated that MCM7 is not only sustained but maintains association with chromatin durin...

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Autores principales: Dianpeng Zheng, Sichao Ye, Xiuyun Wang, Yongjun Zhang, Daoyu Yan, Xiangsheng Cai, Weihong Gao, Hongbo Shan, Yang Gao, Juanjuan Chen, Zhiming Hu, Hongwei Li, Jinlong Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/ad7ef13dadd44128ad853042f16fc5cc
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