Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibition.
Human α-defensins are potent anti-microbial peptides with the ability to neutralize bacterial and viral targets. Single alanine mutagenesis has been used to identify determinants of anti-bacterial activity and binding to bacterial proteins such as anthrax lethal factor. Similar analyses of α-defensi...
Guardado en:
Autores principales: | Victoria R Tenge, Anshu P Gounder, Mayim E Wiens, Wuyuan Lu, Jason G Smith |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/ad892edd516044cd9b0a3422a861febb |
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