Delineation of interfaces on human alpha-defensins critical for human adenovirus and human papillomavirus inhibition.

Human α-defensins are potent anti-microbial peptides with the ability to neutralize bacterial and viral targets. Single alanine mutagenesis has been used to identify determinants of anti-bacterial activity and binding to bacterial proteins such as anthrax lethal factor. Similar analyses of α-defensi...

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Bibliographic Details
Main Authors: Victoria R Tenge, Anshu P Gounder, Mayim E Wiens, Wuyuan Lu, Jason G Smith
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
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Online Access:https://doaj.org/article/ad892edd516044cd9b0a3422a861febb
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