Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?

Background: Bell’s palsy is the most common cause of peripheral facial palsy. The etiology and treatment of Bell’s palsy are still controversial. Previous studies emphasize the role of herpes simplex and herpes zoster viruses in this ailment. The role of Interleukin-10 (IL-10) in Bell’s palsy is ye...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mehdi Maghbooli, Abdolreza Esmaeilzadeh, Fatemeh Karami Zarandi, Arezoo Jafarzadeh, Sajjad Biglari, Nazanin Azizi Shalbaf, Negar Farhoudi
Formato:	article
Lenguaje:	EN
Publicado:	Vilnius University Press 2021
Materias:	Bell’s palsy Interleukin-10 Nerve conduction study Medicine R
Acceso en línea:	https://doaj.org/article/ada309c2a3ce4ed2a03da27f4c84fbf6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ada309c2a3ce4ed2a03da27f4c84fbf6
record_format	dspace
spelling	oai:doaj.org-article:ada309c2a3ce4ed2a03da27f4c84fbf62021-11-09T09:30:03ZIs There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?10.15388/Amed.2021.28.2.151392-01382029-4174https://doaj.org/article/ada309c2a3ce4ed2a03da27f4c84fbf62021-11-01T00:00:00Zhttps://www.journals.vu.lt/AML/article/view/24364https://doaj.org/toc/1392-0138https://doaj.org/toc/2029-4174 Background: Bell’s palsy is the most common cause of peripheral facial palsy. The etiology and treatment of Bell’s palsy are still controversial. Previous studies emphasize the role of herpes simplex and herpes zoster viruses in this ailment. The role of Interleukin-10 (IL-10) in Bell’s palsy is yet unknown, and few studies have shed light on the matter. This study intended to assess the prognostic value of IL-10 and its relation to the intensity of electrodiagnostic abnormalities and evaluate its potential use as a factor for judging the need for medical or surgical interventions. Materials and Methods: 30 patients in the acute phase of Bell’s palsy participated in this study. Peripheral blood samples were obtained for IL-10 assessment within the first 72 hours (before commencing treatment), and a nerve conduction study (NCS) was performed six days after symptom onset. Results: There was no significant correlation between IL-10 serum levels and the severity of nerve conduction pathology in Orbicularis oculi and Orbicularis oris muscles. Also, IL-10 serum levels did not show any meaningful relationships with participants’ age, gender, or symptoms. Conclusion: The IL-10 serum levels are not relevant to the pathology of Bell’s palsy, and the assessment of IL-10 serum levels cannot be used as an alternative to NCS for evaluating the severity of acute Bell’s palsy. Mehdi MaghbooliAbdolreza Esmaeilzadeh Fatemeh Karami ZarandiArezoo Jafarzadeh Sajjad Biglari Nazanin Azizi Shalbaf Negar Farhoudi Vilnius University PressarticleBell’s palsyInterleukin-10Nerve conduction studyMedicineRENActa Medica Lituanica, Vol 28, Iss 2 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Bell’s palsy Interleukin-10 Nerve conduction study Medicine R
spellingShingle	Bell’s palsy Interleukin-10 Nerve conduction study Medicine R Mehdi Maghbooli Abdolreza Esmaeilzadeh Fatemeh Karami Zarandi Arezoo Jafarzadeh Sajjad Biglari Nazanin Azizi Shalbaf Negar Farhoudi Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
description	Background: Bell’s palsy is the most common cause of peripheral facial palsy. The etiology and treatment of Bell’s palsy are still controversial. Previous studies emphasize the role of herpes simplex and herpes zoster viruses in this ailment. The role of Interleukin-10 (IL-10) in Bell’s palsy is yet unknown, and few studies have shed light on the matter. This study intended to assess the prognostic value of IL-10 and its relation to the intensity of electrodiagnostic abnormalities and evaluate its potential use as a factor for judging the need for medical or surgical interventions. Materials and Methods: 30 patients in the acute phase of Bell’s palsy participated in this study. Peripheral blood samples were obtained for IL-10 assessment within the first 72 hours (before commencing treatment), and a nerve conduction study (NCS) was performed six days after symptom onset. Results: There was no significant correlation between IL-10 serum levels and the severity of nerve conduction pathology in Orbicularis oculi and Orbicularis oris muscles. Also, IL-10 serum levels did not show any meaningful relationships with participants’ age, gender, or symptoms. Conclusion: The IL-10 serum levels are not relevant to the pathology of Bell’s palsy, and the assessment of IL-10 serum levels cannot be used as an alternative to NCS for evaluating the severity of acute Bell’s palsy.
format	article
author	Mehdi Maghbooli Abdolreza Esmaeilzadeh Fatemeh Karami Zarandi Arezoo Jafarzadeh Sajjad Biglari Nazanin Azizi Shalbaf Negar Farhoudi
author_facet	Mehdi Maghbooli Abdolreza Esmaeilzadeh Fatemeh Karami Zarandi Arezoo Jafarzadeh Sajjad Biglari Nazanin Azizi Shalbaf Negar Farhoudi
author_sort	Mehdi Maghbooli
title	Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
title_short	Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
title_full	Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
title_fullStr	Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
title_full_unstemmed	Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?
title_sort	is there any relation between serum levels of interleukin-10 and neurophysiological abnormalities in bell’s palsy?
publisher	Vilnius University Press
publishDate	2021
url	https://doaj.org/article/ada309c2a3ce4ed2a03da27f4c84fbf6
work_keys_str_mv	AT mehdimaghbooli isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT abdolrezaesmaeilzadeh isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT fatemehkaramizarandi isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT arezoojafarzadeh isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT sajjadbiglari isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT nazaninazizishalbaf isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy AT negarfarhoudi isthereanyrelationbetweenserumlevelsofinterleukin10andneurophysiologicalabnormalitiesinbellspalsy
_version_	1718441233664180224

Is There Any Relation between Serum Levels of Interleukin-10 and Neurophysiological Abnormalities in Bell’s Palsy?

Ejemplares similares