Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice

Abstract Mutations in the SALL4 gene cause human syndromes with defects in multiple organs. Sall4 expression declines rapidly in post-gastrulation mouse embryos, and our understanding of the requirement of Sall4 in animal development is still limited. To assess the contributions of Sall4 expressing...

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Bibliographic Details
Main Authors: Naoyuki Tahara, Hiroko Kawakami, Teng Zhang, David Zarkower, Yasuhiko Kawakami
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/ada8956bffef4fcd98ae5fa82504f6bc
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