Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells

Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis occurs at the cribriform plate, but not the menin...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Martin Hsu, Aditya Rayasam, Julie A. Kijak, Yun Hwa Choi, Jeffrey S. Harding, Sarah A. Marcus, William J. Karpus, Matyas Sandor, Zsuzsanna Fabry
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:adb4bdd81e9e458aa8bdad35a32985c3
record_format	dspace
spelling	oai:doaj.org-article:adb4bdd81e9e458aa8bdad35a32985c32021-12-02T14:39:41ZNeuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells10.1038/s41467-018-08163-02041-1723https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c32019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08163-0https://doaj.org/toc/2041-1723Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis occurs at the cribriform plate, but not the meninges, and contributes to immune cell and antigen drainage.Martin HsuAditya RayasamJulie A. KijakYun Hwa ChoiJeffrey S. HardingSarah A. MarcusWilliam J. KarpusMatyas SandorZsuzsanna FabryNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Martin Hsu Aditya Rayasam Julie A. Kijak Yun Hwa Choi Jeffrey S. Harding Sarah A. Marcus William J. Karpus Matyas Sandor Zsuzsanna Fabry Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
description	Lymphangiogenesis occurs in the context of systemic inflammation and development but has not been reported for the lymphatics that surround the CNS. Here the authors show that in the context of experimental autoimmune encephatlitis, lymphangiogenesis occurs at the cribriform plate, but not the meninges, and contributes to immune cell and antigen drainage.
format	article
author	Martin Hsu Aditya Rayasam Julie A. Kijak Yun Hwa Choi Jeffrey S. Harding Sarah A. Marcus William J. Karpus Matyas Sandor Zsuzsanna Fabry
author_facet	Martin Hsu Aditya Rayasam Julie A. Kijak Yun Hwa Choi Jeffrey S. Harding Sarah A. Marcus William J. Karpus Matyas Sandor Zsuzsanna Fabry
author_sort	Martin Hsu
title	Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
title_short	Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
title_full	Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
title_fullStr	Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
title_full_unstemmed	Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells
title_sort	neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of cns-derived antigens and immune cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/adb4bdd81e9e458aa8bdad35a32985c3
work_keys_str_mv	AT martinhsu neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT adityarayasam neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT julieakijak neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT yunhwachoi neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT jeffreysharding neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT sarahamarcus neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT williamjkarpus neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT matyassandor neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells AT zsuzsannafabry neuroinflammationinducedlymphangiogenesisnearthecribriformplatecontributestodrainageofcnsderivedantigensandimmunecells
_version_	1718390553552355328

Neuroinflammation-induced lymphangiogenesis near the cribriform plate contributes to drainage of CNS-derived antigens and immune cells

Ejemplares similares