Genetic Association Reveals Protection against Recurrence of <italic toggle="yes">Clostridium difficile</italic> Infection with Bezlotoxumab Treatment

Genetic Association Reveals Protection against Recurrence of <italic toggle="yes">Clostridium difficile</italic> Infection with Bezlotoxumab Treatment

ABSTRACT Bezlotoxumab is a human monoclonal antibody against Clostridium difficile toxin B, indicated to prevent recurrence of C. difficile infection (rCDI) in high-risk adults receiving antibacterial treatment for CDI. An exploratory genome-wide association study investigated whether human genetic...

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Autores principales: Judong Shen, Devan V. Mehrotra, Mary Beth Dorr, Zhen Zeng, Junhua Li, Xun Xu, David Nickle, Emily R. Holzinger, Aparna Chhibber, Mark H. Wilcox, Rebecca L. Blanchard, Peter M. Shaw
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
Clostridium difficile
antibacterials
bezlotoxumab
genomics
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/adb561e16b8649aeaf98ce58ff6ef478
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