Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis

Background: Chronic rhinosinusitis associated with nasal polypi [CRSwNP] is one of the two major chronic rhinosinusitis phenotypes. The histopathological changes of such condition may differ between primary and chronic types.Aim of the work: To differentiate between primary and chronic rhinosinusiti...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wael Fawzy Ismaiel, Ahmed Abd Alrahman Ibrahim, Sami Abdullah Mohammed
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	rhinosinusitis nasal polyposis eosinophilia recurrence Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/adb86fbb7d4a488ba7f6fef6a5c79c10
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:adb86fbb7d4a488ba7f6fef6a5c79c10
record_format	dspace
spelling	oai:doaj.org-article:adb86fbb7d4a488ba7f6fef6a5c79c102021-12-02T15:54:52ZComparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis2636-41742682-378010.21608/ijma.2020.42597.1166https://doaj.org/article/adb86fbb7d4a488ba7f6fef6a5c79c102021-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_121246_608869805fcf7393ba97c311d301ba84.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Chronic rhinosinusitis associated with nasal polypi [CRSwNP] is one of the two major chronic rhinosinusitis phenotypes. The histopathological changes of such condition may differ between primary and chronic types.Aim of the work: To differentiate between primary and chronic rhinosinusitis with polypi through detection of the histopathological changes of nasal mucosa.Patients and Methods: Eighty-five patients with CRSwNP scheduled for functional endoscopic sinus surgery (FESS) were divided into two groups; group (1) 35 patients with primary polyposis, group (2) 50 patients with chronic polyposis. A swab was taken from sinus mucosa during FESS and sent for histopathological investigation.Results: We studied 12 histopathogical findings of spacemen of sinus mucosa and found 7 of them had a significant value in comparison between primary and recurrent CRSwNP. The significant increases in chronic recurrent group (2) than primary group (1) were eosinophilic cell count (p=0.044), eosinophilic cell aggregation (p=0.049), basement membrane thickness (P=0.021), Mucosal ulceration (p=0.002), hyperplastic or papillary change (p=0.029), fibrosis (p=0.002) and fungal element (p=0.003).Conclusion: Histopathological findings of sinus mucosa during FESS operation found to be of great value in differentiating between primary and recurrent CRSwNP, however, further studies on large scale groups were recommended to confirm these results.Wael Fawzy IsmaielAhmed Abd Alrahman IbrahimSami Abdullah MohammedAl-Azhar University, Faculty of Medicine (Damietta)articlerhinosinusitisnasalpolyposiseosinophiliarecurrenceMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 2, Pp 1200-1207 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	rhinosinusitis nasal polyposis eosinophilia recurrence Medicine (General) R5-920
spellingShingle	rhinosinusitis nasal polyposis eosinophilia recurrence Medicine (General) R5-920 Wael Fawzy Ismaiel Ahmed Abd Alrahman Ibrahim Sami Abdullah Mohammed Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
description	Background: Chronic rhinosinusitis associated with nasal polypi [CRSwNP] is one of the two major chronic rhinosinusitis phenotypes. The histopathological changes of such condition may differ between primary and chronic types.Aim of the work: To differentiate between primary and chronic rhinosinusitis with polypi through detection of the histopathological changes of nasal mucosa.Patients and Methods: Eighty-five patients with CRSwNP scheduled for functional endoscopic sinus surgery (FESS) were divided into two groups; group (1) 35 patients with primary polyposis, group (2) 50 patients with chronic polyposis. A swab was taken from sinus mucosa during FESS and sent for histopathological investigation.Results: We studied 12 histopathogical findings of spacemen of sinus mucosa and found 7 of them had a significant value in comparison between primary and recurrent CRSwNP. The significant increases in chronic recurrent group (2) than primary group (1) were eosinophilic cell count (p=0.044), eosinophilic cell aggregation (p=0.049), basement membrane thickness (P=0.021), Mucosal ulceration (p=0.002), hyperplastic or papillary change (p=0.029), fibrosis (p=0.002) and fungal element (p=0.003).Conclusion: Histopathological findings of sinus mucosa during FESS operation found to be of great value in differentiating between primary and recurrent CRSwNP, however, further studies on large scale groups were recommended to confirm these results.
format	article
author	Wael Fawzy Ismaiel Ahmed Abd Alrahman Ibrahim Sami Abdullah Mohammed
author_facet	Wael Fawzy Ismaiel Ahmed Abd Alrahman Ibrahim Sami Abdullah Mohammed
author_sort	Wael Fawzy Ismaiel
title	Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
title_short	Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
title_full	Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
title_fullStr	Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
title_full_unstemmed	Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis
title_sort	comparative histopathological changes between primary versus recurrent rhinosinusitis with nasal polyposis
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/adb86fbb7d4a488ba7f6fef6a5c79c10
work_keys_str_mv	AT waelfawzyismaiel comparativehistopathologicalchangesbetweenprimaryversusrecurrentrhinosinusitiswithnasalpolyposis AT ahmedabdalrahmanibrahim comparativehistopathologicalchangesbetweenprimaryversusrecurrentrhinosinusitiswithnasalpolyposis AT samiabdullahmohammed comparativehistopathologicalchangesbetweenprimaryversusrecurrentrhinosinusitiswithnasalpolyposis
_version_	1718385470341120000

Comparative Histopathological Changes Between Primary Versus Recurrent Rhinosinusitis with Nasal Polyposis

Ejemplares similares