Impact of wet-dry cycling on the phase behavior and compartmentalization properties of complex coacervates

Wet-dry cycling is thought to have enabled the production of molecular building blocks of life. Here, the authors investigate the impact of dehydration/rehydration on RNA-containing complex coacervates, which are membraneless compartments formed by phase separation of polyelectrolyte solutions.

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Auteurs principaux: Hadi M. Fares, Alexander E. Marras, Jeffrey M. Ting, Matthew V. Tirrell, Christine D. Keating
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/adbbebc8e46a4a0f9f1f0c307dd43ce7
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Résumé:Wet-dry cycling is thought to have enabled the production of molecular building blocks of life. Here, the authors investigate the impact of dehydration/rehydration on RNA-containing complex coacervates, which are membraneless compartments formed by phase separation of polyelectrolyte solutions.