Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation
Abstract Connexins play essential roles in lens homeostasis and development. Here, we identified a new role for Cx50 that mediates cell-cell adhesion function. Cx50 enhanced the adhesive capability of AQP0. Interestingly, the expression of Cx50 alone promoted cell adhesion at a comparable level to A...
Enregistré dans:
Auteurs principaux: | Zhengping Hu, Wen Shi, Manuel A. Riquelme, Qian Shi, Sondip Biswas, Woo-Kuen Lo, Thomas W. White, Sumin Gu, Jean X. Jiang |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/adbf4e47e6d44d61a17a14eb20b331b8 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Data on Connexin 43 hemichannels regulation of cellular redox in lens
par: Yumeng Quan, et autres
Publié: (2021) -
Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å
par: Jonathan A. Flores, et autres
Publié: (2020) -
Cell adhesion molecules and exercise
par: Koh Y, et autres
Publié: (2018) -
DIFFERENTIAL LEVELS OF CYTOKINES AND INTERCELLULAR ADHESION MOLECULES AND THEIR DIAGNOSTIC EFFICIENCY IN AUTOIMMUNE AND ONCOLOGICAL THYROID DISEASES
par: S. P. Kazakov
Publié: (2014) -
Initial osteoblast adhesion and subsequent differentiation on zirconia surfaces are regulated by integrins and heparin-sensitive molecule
par: Luo F, et autres
Publié: (2018)