Connexin 50 Functions as an Adhesive Molecule and Promotes Lens Cell Differentiation

Abstract Connexins play essential roles in lens homeostasis and development. Here, we identified a new role for Cx50 that mediates cell-cell adhesion function. Cx50 enhanced the adhesive capability of AQP0. Interestingly, the expression of Cx50 alone promoted cell adhesion at a comparable level to A...

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Auteurs principaux: Zhengping Hu, Wen Shi, Manuel A. Riquelme, Qian Shi, Sondip Biswas, Woo-Kuen Lo, Thomas W. White, Sumin Gu, Jean X. Jiang
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/adbf4e47e6d44d61a17a14eb20b331b8
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