Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults

Clonal haematopoiesis has been thought to occur in less than 10% of individuals younger than 70 years old. Here, the authors use an error corrected next-generation sequencing method to find clonal haematopoiesis in the peripheral blood of 19 of 20 healthy 50–70 year old individuals.

Guardado en:
Detalles Bibliográficos
Autores principales: Andrew L. Young, Grant A. Challen, Brenda M. Birmann, Todd E. Druley
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/adc6b05a48594b9cb165f437521fd659
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:adc6b05a48594b9cb165f437521fd659
record_format dspace
spelling oai:doaj.org-article:adc6b05a48594b9cb165f437521fd6592021-12-02T15:34:10ZClonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults10.1038/ncomms124842041-1723https://doaj.org/article/adc6b05a48594b9cb165f437521fd6592016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12484https://doaj.org/toc/2041-1723Clonal haematopoiesis has been thought to occur in less than 10% of individuals younger than 70 years old. Here, the authors use an error corrected next-generation sequencing method to find clonal haematopoiesis in the peripheral blood of 19 of 20 healthy 50–70 year old individuals.Andrew L. YoungGrant A. ChallenBrenda M. BirmannTodd E. DruleyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrew L. Young
Grant A. Challen
Brenda M. Birmann
Todd E. Druley
Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
description Clonal haematopoiesis has been thought to occur in less than 10% of individuals younger than 70 years old. Here, the authors use an error corrected next-generation sequencing method to find clonal haematopoiesis in the peripheral blood of 19 of 20 healthy 50–70 year old individuals.
format article
author Andrew L. Young
Grant A. Challen
Brenda M. Birmann
Todd E. Druley
author_facet Andrew L. Young
Grant A. Challen
Brenda M. Birmann
Todd E. Druley
author_sort Andrew L. Young
title Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
title_short Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
title_full Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
title_fullStr Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
title_full_unstemmed Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults
title_sort clonal haematopoiesis harbouring aml-associated mutations is ubiquitous in healthy adults
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/adc6b05a48594b9cb165f437521fd659
work_keys_str_mv AT andrewlyoung clonalhaematopoiesisharbouringamlassociatedmutationsisubiquitousinhealthyadults
AT grantachallen clonalhaematopoiesisharbouringamlassociatedmutationsisubiquitousinhealthyadults
AT brendambirmann clonalhaematopoiesisharbouringamlassociatedmutationsisubiquitousinhealthyadults
AT toddedruley clonalhaematopoiesisharbouringamlassociatedmutationsisubiquitousinhealthyadults
_version_ 1718386921260974080

Ejemplares similares