Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control <italic toggle="yes">Mycobacterium tuberculosis</italic> Infection in Macrophages

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Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control <italic toggle="yes">Mycobacterium tuberculosis</italic> Infection in Macrophages

ABSTRACT Mycobacterium tuberculosis (Mtb) causes one of the deadliest infectious diseases worldwide. Upon infection, Mtb is phagocytosed by macrophages and uses its virulence-associated ESX-1 secretion system to modulate the host cell. We showed previously that the ESX-1 secretion system perturbs th...

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Autores principales:	Samantha L. Bell, Kayla L. Lopez, Jeffery S. Cox, Kristin L. Patrick, Robert O. Watson
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2021
Materias:	xenophagy bacterial pathogenesis host-pathogen interactions innate immunity Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/adcda7fd76914fb3b611f58e30465cdc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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