Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics

In order to examine how central amygdala (CE) local circuitry interacts with brain-wide affective states, Wank et al performed gene expression analysis and optogenetic fMRI in mice, using basic nociception as a proxy. They found evidence for diverging roles of two major CE neuronal populations in mo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Isabel Wank, Pinelopi Pliota, Sylvia Badurek, Klaus Kraitsy, Joanna Kaczanowska, Johannes Griessner, Silke Kreitz, Andreas Hess, Wulf Haubensak
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/add3e663f08a42978501e1db0419ed1b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:add3e663f08a42978501e1db0419ed1b
record_format	dspace
spelling	oai:doaj.org-article:add3e663f08a42978501e1db0419ed1b2021-12-02T17:39:49ZCentral amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics10.1038/s42003-021-02262-32399-3642https://doaj.org/article/add3e663f08a42978501e1db0419ed1b2021-06-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02262-3https://doaj.org/toc/2399-3642In order to examine how central amygdala (CE) local circuitry interacts with brain-wide affective states, Wank et al performed gene expression analysis and optogenetic fMRI in mice, using basic nociception as a proxy. They found evidence for diverging roles of two major CE neuronal populations in modulating global brain states, which impacts on aversive processing and nocifensive behaviour.Isabel WankPinelopi PliotaSylvia BadurekKlaus KraitsyJoanna KaczanowskaJohannes GriessnerSilke KreitzAndreas HessWulf HaubensakNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Isabel Wank Pinelopi Pliota Sylvia Badurek Klaus Kraitsy Joanna Kaczanowska Johannes Griessner Silke Kreitz Andreas Hess Wulf Haubensak Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
description	In order to examine how central amygdala (CE) local circuitry interacts with brain-wide affective states, Wank et al performed gene expression analysis and optogenetic fMRI in mice, using basic nociception as a proxy. They found evidence for diverging roles of two major CE neuronal populations in modulating global brain states, which impacts on aversive processing and nocifensive behaviour.
format	article
author	Isabel Wank Pinelopi Pliota Sylvia Badurek Klaus Kraitsy Joanna Kaczanowska Johannes Griessner Silke Kreitz Andreas Hess Wulf Haubensak
author_facet	Isabel Wank Pinelopi Pliota Sylvia Badurek Klaus Kraitsy Joanna Kaczanowska Johannes Griessner Silke Kreitz Andreas Hess Wulf Haubensak
author_sort	Isabel Wank
title	Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
title_short	Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
title_full	Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
title_fullStr	Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
title_full_unstemmed	Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
title_sort	central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/add3e663f08a42978501e1db0419ed1b
work_keys_str_mv	AT isabelwank centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT pinelopipliota centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT sylviabadurek centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT klauskraitsy centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT joannakaczanowska centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT johannesgriessner centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT silkekreitz centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT andreashess centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics AT wulfhaubensak centralamygdalacircuitrymodulatesnociceptiveprocessingthroughdifferentialhierarchicalinteractionwithaffectivenetworkdynamics
_version_	1718379781849874432

Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics

Ejemplares similares