Audiotactile interactions in the mouse cochlear nucleus

Abstract Multisensory integration of auditory and tactile information occurs already at the level of the cochlear nucleus. Rodents use their whiskers for tactile perception to guide them in their exploration of the world. As nocturnal animals with relatively poor vision, audiotactile interactions ar...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Josephine Ansorge, Calvin Wu, Susan E. Shore, Patrik Krieger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/add96494966c453f97bfc50d05d6ca40
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:add96494966c453f97bfc50d05d6ca40
record_format	dspace
spelling	oai:doaj.org-article:add96494966c453f97bfc50d05d6ca402021-12-02T11:45:01ZAudiotactile interactions in the mouse cochlear nucleus10.1038/s41598-021-86236-92045-2322https://doaj.org/article/add96494966c453f97bfc50d05d6ca402021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86236-9https://doaj.org/toc/2045-2322Abstract Multisensory integration of auditory and tactile information occurs already at the level of the cochlear nucleus. Rodents use their whiskers for tactile perception to guide them in their exploration of the world. As nocturnal animals with relatively poor vision, audiotactile interactions are of great importance for this species. Here, the influence of whisker deflections on sound-evoked spiking in the cochlear nucleus was investigated in vivo in anesthetized mice. Multichannel, silicon-probe electrophysiological recordings were obtained from both the dorsal and ventral cochlear nucleus. Whisker deflections evoked an increased spiking activity in fusiform cells of the dorsal cochlear nucleus and t-stellate cells in ventral cochlear nucleus, whereas bushy cells in the ventral cochlear nucleus showed a more variable response. The response to broadband noise stimulation increased in fusiform cells and primary-like bushy cells when the sound stimulation was preceded (~ 20 ms) by whisker stimulation. Multi-sensory integration of auditory and whisker input can thus occur already in this early brainstem nucleus, emphasizing the importance of early integration of auditory and somatosensory information.Josephine AnsorgeCalvin WuSusan E. ShorePatrik KriegerNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Josephine Ansorge Calvin Wu Susan E. Shore Patrik Krieger Audiotactile interactions in the mouse cochlear nucleus
description	Abstract Multisensory integration of auditory and tactile information occurs already at the level of the cochlear nucleus. Rodents use their whiskers for tactile perception to guide them in their exploration of the world. As nocturnal animals with relatively poor vision, audiotactile interactions are of great importance for this species. Here, the influence of whisker deflections on sound-evoked spiking in the cochlear nucleus was investigated in vivo in anesthetized mice. Multichannel, silicon-probe electrophysiological recordings were obtained from both the dorsal and ventral cochlear nucleus. Whisker deflections evoked an increased spiking activity in fusiform cells of the dorsal cochlear nucleus and t-stellate cells in ventral cochlear nucleus, whereas bushy cells in the ventral cochlear nucleus showed a more variable response. The response to broadband noise stimulation increased in fusiform cells and primary-like bushy cells when the sound stimulation was preceded (~ 20 ms) by whisker stimulation. Multi-sensory integration of auditory and whisker input can thus occur already in this early brainstem nucleus, emphasizing the importance of early integration of auditory and somatosensory information.
format	article
author	Josephine Ansorge Calvin Wu Susan E. Shore Patrik Krieger
author_facet	Josephine Ansorge Calvin Wu Susan E. Shore Patrik Krieger
author_sort	Josephine Ansorge
title	Audiotactile interactions in the mouse cochlear nucleus
title_short	Audiotactile interactions in the mouse cochlear nucleus
title_full	Audiotactile interactions in the mouse cochlear nucleus
title_fullStr	Audiotactile interactions in the mouse cochlear nucleus
title_full_unstemmed	Audiotactile interactions in the mouse cochlear nucleus
title_sort	audiotactile interactions in the mouse cochlear nucleus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/add96494966c453f97bfc50d05d6ca40
work_keys_str_mv	AT josephineansorge audiotactileinteractionsinthemousecochlearnucleus AT calvinwu audiotactileinteractionsinthemousecochlearnucleus AT susaneshore audiotactileinteractionsinthemousecochlearnucleus AT patrikkrieger audiotactileinteractionsinthemousecochlearnucleus
_version_	1718395303808204800

Audiotactile interactions in the mouse cochlear nucleus

Ejemplares similares