Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

Preimplantation embryos undergo extensive transcriptomic and epigenomic remodeling. Here the authors assay open chromatin in bovine oocytes, embryos, and embryonic stem cells, and compare the transcriptomes and epigenomes of cattle, human and mouse embryos, revealing species-specific regulation of g...

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Autores principales:	Michelle M. Halstead, Xin Ma, Chuan Zhou, Richard M. Schultz, Pablo J. Ross
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/adda09c2b03041b794820756fb6f469e
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spelling	oai:doaj.org-article:adda09c2b03041b794820756fb6f469e2021-12-02T18:02:33ZChromatin remodeling in bovine embryos indicates species-specific regulation of genome activation10.1038/s41467-020-18508-32041-1723https://doaj.org/article/adda09c2b03041b794820756fb6f469e2020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18508-3https://doaj.org/toc/2041-1723Preimplantation embryos undergo extensive transcriptomic and epigenomic remodeling. Here the authors assay open chromatin in bovine oocytes, embryos, and embryonic stem cells, and compare the transcriptomes and epigenomes of cattle, human and mouse embryos, revealing species-specific regulation of genome activation.Michelle M. HalsteadXin MaChuan ZhouRichard M. SchultzPablo J. RossNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Michelle M. Halstead Xin Ma Chuan Zhou Richard M. Schultz Pablo J. Ross Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
description	Preimplantation embryos undergo extensive transcriptomic and epigenomic remodeling. Here the authors assay open chromatin in bovine oocytes, embryos, and embryonic stem cells, and compare the transcriptomes and epigenomes of cattle, human and mouse embryos, revealing species-specific regulation of genome activation.
format	article
author	Michelle M. Halstead Xin Ma Chuan Zhou Richard M. Schultz Pablo J. Ross
author_facet	Michelle M. Halstead Xin Ma Chuan Zhou Richard M. Schultz Pablo J. Ross
author_sort	Michelle M. Halstead
title	Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
title_short	Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
title_full	Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
title_fullStr	Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
title_full_unstemmed	Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
title_sort	chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/adda09c2b03041b794820756fb6f469e
work_keys_str_mv	AT michellemhalstead chromatinremodelinginbovineembryosindicatesspeciesspecificregulationofgenomeactivation AT xinma chromatinremodelinginbovineembryosindicatesspeciesspecificregulationofgenomeactivation AT chuanzhou chromatinremodelinginbovineembryosindicatesspeciesspecificregulationofgenomeactivation AT richardmschultz chromatinremodelinginbovineembryosindicatesspeciesspecificregulationofgenomeactivation AT pablojross chromatinremodelinginbovineembryosindicatesspeciesspecificregulationofgenomeactivation
_version_	1718378889501212672

Chromatin remodeling in bovine embryos indicates species-specific regulation of genome activation

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