Nannochloropsis oceanica as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats

The microalgal genus Nannochloropsis has broad applicability to produce biofuels, animal feed supplements and other value-added products including proteins, carotenoids and lipids. This study investigated a potential role of N. oceanica in the reversal of metabo...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ryan du Preez, Marwan E. Majzoub, Torsten Thomas, Sunil K. Panchal, Lindsay Brown
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	<i>Nannochloropsis oceanica</i> microalgae metabolic syndrome gut microbiota eicosapentaenoic acid Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/adddd03433ce466b96224cae996c19c4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:adddd03433ce466b96224cae996c19c4
record_format	dspace
spelling	oai:doaj.org-article:adddd03433ce466b96224cae996c19c42021-11-25T18:35:52Z<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats10.3390/nu131139912072-6643https://doaj.org/article/adddd03433ce466b96224cae996c19c42021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6643/13/11/3991https://doaj.org/toc/2072-6643The microalgal genus <i>Nannochloropsis</i> has broad applicability to produce biofuels, animal feed supplements and other value-added products including proteins, carotenoids and lipids. This study investigated a potential role of <i>N. oceanica</i> in the reversal of metabolic syndrome. Male Wistar rats (<i>n</i> = 48) were divided into four groups in a 16-week protocol. Two groups were fed either corn starch or high-carbohydrate, high-fat diets (C and H, respectively) for the full 16 weeks. The other two groups received C and H diets for eight weeks and then received 5% freeze-dried <i>N. oceanica</i> in these diets for the final eight weeks (CN and HN, respectively) of the protocol. The H diet was high in fructose and sucrose, together with increased saturated and <i>trans</i> fats. H rats developed obesity, hypertension, dyslipidaemia, fatty liver disease and left ventricular fibrosis. <i>N. oceanica</i> increased lean mass in CN and HN rats, possibly due to the increased protein intake, and decreased fat mass in HN rats. Intervention with <i>N. oceanica</i> did not change cardiovascular, liver and metabolic parameters or gut structure. The relative abundance of Oxyphotobacteria in the gut microbiota was increased. <i>N. oceanica</i> may be an effective functional food against metabolic syndrome as a sustainable protein source.Ryan du PreezMarwan E. MajzoubTorsten ThomasSunil K. PanchalLindsay BrownMDPI AGarticle<i>Nannochloropsis oceanica</i>microalgaemetabolic syndromegut microbiotaeicosapentaenoic acidNutrition. Foods and food supplyTX341-641ENNutrients, Vol 13, Iss 3991, p 3991 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	<i>Nannochloropsis oceanica</i> microalgae metabolic syndrome gut microbiota eicosapentaenoic acid Nutrition. Foods and food supply TX341-641
spellingShingle	<i>Nannochloropsis oceanica</i> microalgae metabolic syndrome gut microbiota eicosapentaenoic acid Nutrition. Foods and food supply TX341-641 Ryan du Preez Marwan E. Majzoub Torsten Thomas Sunil K. Panchal Lindsay Brown <i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
description	The microalgal genus <i>Nannochloropsis</i> has broad applicability to produce biofuels, animal feed supplements and other value-added products including proteins, carotenoids and lipids. This study investigated a potential role of <i>N. oceanica</i> in the reversal of metabolic syndrome. Male Wistar rats (<i>n</i> = 48) were divided into four groups in a 16-week protocol. Two groups were fed either corn starch or high-carbohydrate, high-fat diets (C and H, respectively) for the full 16 weeks. The other two groups received C and H diets for eight weeks and then received 5% freeze-dried <i>N. oceanica</i> in these diets for the final eight weeks (CN and HN, respectively) of the protocol. The H diet was high in fructose and sucrose, together with increased saturated and <i>trans</i> fats. H rats developed obesity, hypertension, dyslipidaemia, fatty liver disease and left ventricular fibrosis. <i>N. oceanica</i> increased lean mass in CN and HN rats, possibly due to the increased protein intake, and decreased fat mass in HN rats. Intervention with <i>N. oceanica</i> did not change cardiovascular, liver and metabolic parameters or gut structure. The relative abundance of Oxyphotobacteria in the gut microbiota was increased. <i>N. oceanica</i> may be an effective functional food against metabolic syndrome as a sustainable protein source.
format	article
author	Ryan du Preez Marwan E. Majzoub Torsten Thomas Sunil K. Panchal Lindsay Brown
author_facet	Ryan du Preez Marwan E. Majzoub Torsten Thomas Sunil K. Panchal Lindsay Brown
author_sort	Ryan du Preez
title	<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
title_short	<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
title_full	<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
title_fullStr	<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
title_full_unstemmed	<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats
title_sort	<i>nannochloropsis oceanica</i> as a microalgal food intervention in diet-induced metabolic syndrome in rats
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/adddd03433ce466b96224cae996c19c4
work_keys_str_mv	AT ryandupreez inannochloropsisoceanicaiasamicroalgalfoodinterventionindietinducedmetabolicsyndromeinrats AT marwanemajzoub inannochloropsisoceanicaiasamicroalgalfoodinterventionindietinducedmetabolicsyndromeinrats AT torstenthomas inannochloropsisoceanicaiasamicroalgalfoodinterventionindietinducedmetabolicsyndromeinrats AT sunilkpanchal inannochloropsisoceanicaiasamicroalgalfoodinterventionindietinducedmetabolicsyndromeinrats AT lindsaybrown inannochloropsisoceanicaiasamicroalgalfoodinterventionindietinducedmetabolicsyndromeinrats
_version_	1718410971426324480

<i>Nannochloropsis oceanica</i> as a Microalgal Food Intervention in Diet-Induced Metabolic Syndrome in Rats

Ejemplares similares