Structure of human RNA polymerase III
The eukaryotic RNA Polymerase III transcribes tRNAs, some ribosomal and spliceosomal RNAs. Here, the authors resolve a cryo-EM structure of human RNA Polymerase III in its apo form and complemented it with crystal structures and SAXS analysis of RPC5, revealing insights into the molecular mechanisms...
Saved in:
Main Authors: | Ewan Phillip Ramsay, Guillermo Abascal-Palacios, Julia L. Daiß, Helen King, Jerome Gouge, Michael Pilsl, Fabienne Beuron, Edward Morris, Philip Gunkel, Christoph Engel, Alessandro Vannini |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/addf731bc84249d4a4c0c47a0f5420f5 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes
by: Guillermo Abascal-Palacios, et al.
Published: (2021) -
Molecular mechanisms of Bdp1 in TFIIIB assembly and RNA polymerase III transcription initiation
by: Jerome Gouge, et al.
Published: (2017) -
DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability
by: Kevin Kramm, et al.
Published: (2020) -
Structural basis of RNA polymerase I pre-initiation complex formation and promoter melting
by: Michael Pilsl, et al.
Published: (2020) -
Conserved strategies of RNA polymerase I hibernation and activation
by: Florian B. Heiss, et al.
Published: (2021)