A progesterone biosensor derived from microbial screening
Bacteria represent an unexploited reservoir of biosensing proteins. Here the authors use genomic screens and functional assays to isolate a progesterone sensing allosteric transcription factor and use a FRET-based method to develop an optical progesterone sensor.
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Nature Portfolio
2020
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| Acceso en línea: | https://doaj.org/article/ade403a0c51440ca984d5841402f815b |
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oai:doaj.org-article:ade403a0c51440ca984d5841402f815b2021-12-02T15:39:10ZA progesterone biosensor derived from microbial screening10.1038/s41467-020-14942-52041-1723https://doaj.org/article/ade403a0c51440ca984d5841402f815b2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14942-5https://doaj.org/toc/2041-1723Bacteria represent an unexploited reservoir of biosensing proteins. Here the authors use genomic screens and functional assays to isolate a progesterone sensing allosteric transcription factor and use a FRET-based method to develop an optical progesterone sensor.Chloé GrazonR C. BaerUroš KuzmanovićThuy NguyenMingfu ChenMarjon ZamaniMargaret ChernPatricia AquinoXiaoman ZhangSébastien LecommandouxAndy FanMario CabodiCatherine KlapperichMark W. GrinstaffAllison M. DennisJames E. GalaganNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Chloé Grazon R C. Baer Uroš Kuzmanović Thuy Nguyen Mingfu Chen Marjon Zamani Margaret Chern Patricia Aquino Xiaoman Zhang Sébastien Lecommandoux Andy Fan Mario Cabodi Catherine Klapperich Mark W. Grinstaff Allison M. Dennis James E. Galagan A progesterone biosensor derived from microbial screening |
| description |
Bacteria represent an unexploited reservoir of biosensing proteins. Here the authors use genomic screens and functional assays to isolate a progesterone sensing allosteric transcription factor and use a FRET-based method to develop an optical progesterone sensor. |
| format |
article |
| author |
Chloé Grazon R C. Baer Uroš Kuzmanović Thuy Nguyen Mingfu Chen Marjon Zamani Margaret Chern Patricia Aquino Xiaoman Zhang Sébastien Lecommandoux Andy Fan Mario Cabodi Catherine Klapperich Mark W. Grinstaff Allison M. Dennis James E. Galagan |
| author_facet |
Chloé Grazon R C. Baer Uroš Kuzmanović Thuy Nguyen Mingfu Chen Marjon Zamani Margaret Chern Patricia Aquino Xiaoman Zhang Sébastien Lecommandoux Andy Fan Mario Cabodi Catherine Klapperich Mark W. Grinstaff Allison M. Dennis James E. Galagan |
| author_sort |
Chloé Grazon |
| title |
A progesterone biosensor derived from microbial screening |
| title_short |
A progesterone biosensor derived from microbial screening |
| title_full |
A progesterone biosensor derived from microbial screening |
| title_fullStr |
A progesterone biosensor derived from microbial screening |
| title_full_unstemmed |
A progesterone biosensor derived from microbial screening |
| title_sort |
progesterone biosensor derived from microbial screening |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/ade403a0c51440ca984d5841402f815b |
| work_keys_str_mv |
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