Instructing cells with programmable peptide DNA hybrids

The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell orga...

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Autores principales: Ronit Freeman, Nicholas Stephanopoulos, Zaida Álvarez, Jacob A Lewis, Shantanu Sur, Chris M Serrano, Job Boekhoven, Sungsoo S. Lee, Samuel I. Stupp
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/adec0b74d8f044eba6a16b4902f1965a
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spelling oai:doaj.org-article:adec0b74d8f044eba6a16b4902f1965a2021-12-02T14:42:26ZInstructing cells with programmable peptide DNA hybrids10.1038/ncomms159822041-1723https://doaj.org/article/adec0b74d8f044eba6a16b4902f1965a2017-07-01T00:00:00Zhttps://doi.org/10.1038/ncomms15982https://doaj.org/toc/2041-1723The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation.Ronit FreemanNicholas StephanopoulosZaida ÁlvarezJacob A LewisShantanu SurChris M SerranoJob BoekhovenSungsoo S. LeeSamuel I. StuppNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Ronit Freeman
Nicholas Stephanopoulos
Zaida Álvarez
Jacob A Lewis
Shantanu Sur
Chris M Serrano
Job Boekhoven
Sungsoo S. Lee
Samuel I. Stupp
Instructing cells with programmable peptide DNA hybrids
description The extracellular matrix can affect cell behaviour both physically and biochemically. Here, the authors developed a substrate that is based on peptides and nucleic acids hybrids that can dynamically present signals upon demand which regulate cell adhesion and migration, thereby controlling cell organisation.
format article
author Ronit Freeman
Nicholas Stephanopoulos
Zaida Álvarez
Jacob A Lewis
Shantanu Sur
Chris M Serrano
Job Boekhoven
Sungsoo S. Lee
Samuel I. Stupp
author_facet Ronit Freeman
Nicholas Stephanopoulos
Zaida Álvarez
Jacob A Lewis
Shantanu Sur
Chris M Serrano
Job Boekhoven
Sungsoo S. Lee
Samuel I. Stupp
author_sort Ronit Freeman
title Instructing cells with programmable peptide DNA hybrids
title_short Instructing cells with programmable peptide DNA hybrids
title_full Instructing cells with programmable peptide DNA hybrids
title_fullStr Instructing cells with programmable peptide DNA hybrids
title_full_unstemmed Instructing cells with programmable peptide DNA hybrids
title_sort instructing cells with programmable peptide dna hybrids
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/adec0b74d8f044eba6a16b4902f1965a
work_keys_str_mv AT ronitfreeman instructingcellswithprogrammablepeptidednahybrids
AT nicholasstephanopoulos instructingcellswithprogrammablepeptidednahybrids
AT zaidaalvarez instructingcellswithprogrammablepeptidednahybrids
AT jacobalewis instructingcellswithprogrammablepeptidednahybrids
AT shantanusur instructingcellswithprogrammablepeptidednahybrids
AT chrismserrano instructingcellswithprogrammablepeptidednahybrids
AT jobboekhoven instructingcellswithprogrammablepeptidednahybrids
AT sungsooslee instructingcellswithprogrammablepeptidednahybrids
AT samuelistupp instructingcellswithprogrammablepeptidednahybrids
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